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Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or Necrosis

Drug-induced liver injury (DILI) can broadly be divided into predictable and dose dependent such as acetaminophen (APAP) and unpredictable or idiosyncratic DILI (IDILI). Liver injury from drug hepatotoxicity (whether idiosyncratic or predictable) results in hepatocyte cell death and inflammation. Th...

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Detalles Bibliográficos
Autores principales:	Iorga, Andrea, Dara, Lily, Kaplowitz, Neil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454931/ https://www.ncbi.nlm.nih.gov/pubmed/28486401 http://dx.doi.org/10.3390/ijms18051018

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