Cargando…
Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or Necrosis
Drug-induced liver injury (DILI) can broadly be divided into predictable and dose dependent such as acetaminophen (APAP) and unpredictable or idiosyncratic DILI (IDILI). Liver injury from drug hepatotoxicity (whether idiosyncratic or predictable) results in hepatocyte cell death and inflammation. Th...
Autores principales: | Iorga, Andrea, Dara, Lily, Kaplowitz, Neil |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454931/ https://www.ncbi.nlm.nih.gov/pubmed/28486401 http://dx.doi.org/10.3390/ijms18051018 |
Ejemplares similares
-
Cell Death in Liver Diseases: A Review
por: Shojaie, Layla, et al.
Publicado: (2020) -
Mechanisms of immune checkpoint inhibitor-mediated liver injury
por: Shojaie, Layla, et al.
Publicado: (2021) -
Questions and controversies: the role of necroptosis in liver disease
por: Dara, Lily, et al.
Publicado: (2016) -
Apoptosis and Necrosis: Two Types of Cell Death in Alcoholic Liver Disease
por: Nanji, Amin A., et al.
Publicado: (1997) -
Deriving time-concordant event cascades from gene expression data: A case study for Drug-Induced Liver Injury (DILI)
por: Liu, Anika, et al.
Publicado: (2022)