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Aldosterone and Mineralocorticoid Receptors—Physiology and Pathophysiology

Aldosterone is a uniquely terrestrial hormone, first appearing in lungfish, which have both gills and lungs. Mineralocorticoid receptors (MRs), on the other hand, evolved much earlier, and are found in cartilaginous and bony fish, presumptive ligand cortisol. MRs have equivalent high affinity for al...

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Detalles Bibliográficos
Autor principal: Funder, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454944/
https://www.ncbi.nlm.nih.gov/pubmed/28492512
http://dx.doi.org/10.3390/ijms18051032