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Selective Expression of Flt3 within the Mouse Hematopoietic Stem Cell Compartment
The fms-like tyrosine kinase 3 (Flt3) is a cell surface receptor that is expressed by various hematopoietic progenitor cells (HPC) and Flt3-activating mutations are commonly present in acute myeloid and lymphoid leukemias. These findings underscore the importance of Flt3 to steady-state and malignan...
Autores principales: | Mooney, Ciaran James, Cunningham, Alan, Tsapogas, Panagiotis, Toellner, Kai-Michael, Brown, Geoffrey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454949/ https://www.ncbi.nlm.nih.gov/pubmed/28498310 http://dx.doi.org/10.3390/ijms18051037 |
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