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Osteopontin Deficiency Suppresses Intestinal Tumor Development in Apc-Deficient Min Mice

Osteopontin (OPN) is a secreted phosphoglycoprotein, and is a transcriptional target of aberrant Wnt signaling. OPN is upregulated in human colon cancers, and is suggested to enhance cancer progression. In this study, the effect of deficiency of OPN on intestinal tumor development in Apc-deficient M...

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Detalles Bibliográficos
Autores principales:	Ishigamori, Rikako, Komiya, Masami, Takasu, Shinji, Mutoh, Michihiro, Imai, Toshio, Takahashi, Mami
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454970/ https://www.ncbi.nlm.nih.gov/pubmed/28505114 http://dx.doi.org/10.3390/ijms18051058

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