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Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample

Clinical genetic testing (CGT) of children with autism spectrum disorder (ASD) may have positive and negative effects. Knowledge about parents’ attitudes is needed to ensure good involvement of caregivers, which is crucial for accurate diagnosis and effective clinical management. This study aimed to...

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Autores principales: Johannessen, Jarle, Nærland, Terje, Hope, Sigrun, Torske, Tonje, Høyland, Anne Lise, Strohmaier, Jana, Heiberg, Arvid, Rietschel, Marcella, Djurovic, Srdjan, Andreassen, Ole A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454987/
https://www.ncbi.nlm.nih.gov/pubmed/28524073
http://dx.doi.org/10.3390/ijms18051078
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author Johannessen, Jarle
Nærland, Terje
Hope, Sigrun
Torske, Tonje
Høyland, Anne Lise
Strohmaier, Jana
Heiberg, Arvid
Rietschel, Marcella
Djurovic, Srdjan
Andreassen, Ole A.
author_facet Johannessen, Jarle
Nærland, Terje
Hope, Sigrun
Torske, Tonje
Høyland, Anne Lise
Strohmaier, Jana
Heiberg, Arvid
Rietschel, Marcella
Djurovic, Srdjan
Andreassen, Ole A.
author_sort Johannessen, Jarle
collection PubMed
description Clinical genetic testing (CGT) of children with autism spectrum disorder (ASD) may have positive and negative effects. Knowledge about parents’ attitudes is needed to ensure good involvement of caregivers, which is crucial for accurate diagnosis and effective clinical management. This study aimed to assess parents’ attitudes toward CGT for ASD. Parent members of the Norwegian Autism Society were given a previously untested questionnaire and 1455 answered. Linear regression analyses were conducted to evaluate contribution of parent and child characteristics to attitude statements. Provided it could contribute to a casual explanation of their child’s ASD, 76% would undergo CGT. If it would improve the possibilities for early interventions, 74% were positive to CGT. Between 49–67% agreed that CGT could have a negative impact on health insurance, increase their concern for the child’s future and cause family conflicts. Parents against CGT (9%) were less optimistic regarding positive effects, but not more concerned with negative impacts. The severity of the children’s ASD diagnosis had a weak positive association with parent’s positive attitudes to CGT (p-values range from <0.001 to 0.975). Parents prefer that CGT is offered to those having a child with ASD (65%), when the child’s development deviates from normal (48%), or before pregnancy (36%). A majority of the parents of children with ASD are positive to CGT due to possibilities for an etiological explanation.
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spelling pubmed-54549872017-06-08 Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample Johannessen, Jarle Nærland, Terje Hope, Sigrun Torske, Tonje Høyland, Anne Lise Strohmaier, Jana Heiberg, Arvid Rietschel, Marcella Djurovic, Srdjan Andreassen, Ole A. Int J Mol Sci Article Clinical genetic testing (CGT) of children with autism spectrum disorder (ASD) may have positive and negative effects. Knowledge about parents’ attitudes is needed to ensure good involvement of caregivers, which is crucial for accurate diagnosis and effective clinical management. This study aimed to assess parents’ attitudes toward CGT for ASD. Parent members of the Norwegian Autism Society were given a previously untested questionnaire and 1455 answered. Linear regression analyses were conducted to evaluate contribution of parent and child characteristics to attitude statements. Provided it could contribute to a casual explanation of their child’s ASD, 76% would undergo CGT. If it would improve the possibilities for early interventions, 74% were positive to CGT. Between 49–67% agreed that CGT could have a negative impact on health insurance, increase their concern for the child’s future and cause family conflicts. Parents against CGT (9%) were less optimistic regarding positive effects, but not more concerned with negative impacts. The severity of the children’s ASD diagnosis had a weak positive association with parent’s positive attitudes to CGT (p-values range from <0.001 to 0.975). Parents prefer that CGT is offered to those having a child with ASD (65%), when the child’s development deviates from normal (48%), or before pregnancy (36%). A majority of the parents of children with ASD are positive to CGT due to possibilities for an etiological explanation. MDPI 2017-05-18 /pmc/articles/PMC5454987/ /pubmed/28524073 http://dx.doi.org/10.3390/ijms18051078 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Johannessen, Jarle
Nærland, Terje
Hope, Sigrun
Torske, Tonje
Høyland, Anne Lise
Strohmaier, Jana
Heiberg, Arvid
Rietschel, Marcella
Djurovic, Srdjan
Andreassen, Ole A.
Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample
title Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample
title_full Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample
title_fullStr Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample
title_full_unstemmed Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample
title_short Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample
title_sort parents’ attitudes toward clinical genetic testing for autism spectrum disorder—data from a norwegian sample
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454987/
https://www.ncbi.nlm.nih.gov/pubmed/28524073
http://dx.doi.org/10.3390/ijms18051078
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