Autophagy Regulates Proteasome Inhibitor-Induced Pigmentation in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells

The impairment of autophagic and proteasomal cleansing together with changes in pigmentation has been documented in retinal pigment epithelial (RPE) cell degeneration. However, the function and co-operation of these mechanisms in melanosome-containing RPE cells is still unclear. We show that inhibit...

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Detalles Bibliográficos
Autores principales: Juuti-Uusitalo, Kati, Koskela, Ali, Kivinen, Niko, Viiri, Johanna, Hyttinen, Juha M. T., Reinisalo, Mika, Koistinen, Arto, Uusitalo, Hannu, Sinha, Debasish, Skottman, Heli, Kaarniranta, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454998/
https://www.ncbi.nlm.nih.gov/pubmed/28534814
http://dx.doi.org/10.3390/ijms18051089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454998/
https://www.ncbi.nlm.nih.gov/pubmed/28534814
http://dx.doi.org/10.3390/ijms18051089

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