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SIRT1 ameliorates oxidative stress induced neural cell death and is down-regulated in Parkinson’s disease

BACKGROUND: Sirtuins (SIRTs) are NAD(+) dependent lysine deacetylases which are conserved from bacteria to humans and have been associated with longevity and lifespan extension. SIRT1, the best studied mammalian SIRT is involved in many physiological and pathological processes and changes in SIRT1 h...

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Detalles Bibliográficos
Autores principales:	Singh, Preeti, Hanson, Peter S., Morris, Christopher M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455114/ https://www.ncbi.nlm.nih.gov/pubmed/28578695 http://dx.doi.org/10.1186/s12868-017-0364-1

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