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The Histone Deacetylase Inhibitor JAHA Down-Regulates pERK and Global DNA Methylation in MDA-MB231 Breast Cancer Cells
The histone deacetylase inhibitor N(1)-(ferrocenyl)-N(8)-hydroxyoctanediamide (JAHA) down-regulates extracellular-signal-regulated kinase (ERK) and its activated form in triple-negative MDA-MB231 breast cancer cells after 18 h and up to 30 h of treatment, and to a lesser extent AKT and phospho-AKT a...
Autores principales: | Librizzi, Mariangela, Chiarelli, Roberto, Bosco, Liana, Sansook, Supojjanee, Gascon, Jose M., Spencer, John, Caradonna, Fabio, Luparello, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455366/ https://www.ncbi.nlm.nih.gov/pubmed/28793617 http://dx.doi.org/10.3390/ma8105358 |
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