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Integrating Microtissues in Nanofiber Scaffolds for Regenerative Nanomedicine

A new generation of biomaterials focus on smart materials incorporating cells. Here, we describe a novel generation of synthetic nanofibrous implant functionalized with living microtissues for regenerative nanomedicine. The strategy designed here enhances the effectiveness of therapeutic implants co...

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Detalles Bibliográficos
Autores principales: Keller, Laetitia, Wagner, Quentin, Offner, Damien, Eap, Sandy, Musset, Anne-Marie, Arruebo, Manuel, Kelm, Jens M., Schwinté, Pascale, Benkirane-Jessel, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455384/
https://www.ncbi.nlm.nih.gov/pubmed/28793604
http://dx.doi.org/10.3390/ma8105342
Descripción
Sumario:A new generation of biomaterials focus on smart materials incorporating cells. Here, we describe a novel generation of synthetic nanofibrous implant functionalized with living microtissues for regenerative nanomedicine. The strategy designed here enhances the effectiveness of therapeutic implants compared to current approaches used in the clinic today based on single cells added to the implant.