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Multicenter, Phase III, Randomized, Double-Blind, Placebo-Controlled Trial of Pravastatin Added to First-Line Standard Chemotherapy in Small-Cell Lung Cancer (LUNGSTAR)
PURPOSE: Treating small-cell lung cancer (SCLC) remains a therapeutic challenge. Experimental studies show that statins exert additive effects with agents, such as cisplatin, to impair tumor growth, and observational studies suggest that statins combined with anticancer therapies delay relapse and p...
Autores principales: | Seckl, Michael J., Ottensmeier, Christian H., Cullen, Michael, Schmid, Peter, Ngai, Yenting, Muthukumar, Dakshinamoorthy, Thompson, Joyce, Harden, Susan, Middleton, Gary, Fife, Kate M., Crosse, Barbara, Taylor, Paul, Nash, Stephen, Hackshaw, Allan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Clinical Oncology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455702/ https://www.ncbi.nlm.nih.gov/pubmed/28240967 http://dx.doi.org/10.1200/JCO.2016.69.7391 |
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