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Hotspots of homologous recombination in the human genome: not all homologous sequences are equal
Homologous recombination between alleles or non-allelic paralogous sequences does not occur uniformly but is concentrated in 'hotspots' with high recombination rates. Recent studies of these hotspots show that they do not share common sequence motifs, but they do have other features in com...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545587/ https://www.ncbi.nlm.nih.gov/pubmed/15461806 http://dx.doi.org/10.1186/gb-2004-5-10-242 |
| _version_ | 1782122203325661184 |
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| author | Lupski, James R |
| author_facet | Lupski, James R |
| author_sort | Lupski, James R |
| collection | PubMed |
| description | Homologous recombination between alleles or non-allelic paralogous sequences does not occur uniformly but is concentrated in 'hotspots' with high recombination rates. Recent studies of these hotspots show that they do not share common sequence motifs, but they do have other features in common. |
| format | Text |
| id | pubmed-545587 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2004 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-5455872005-01-26 Hotspots of homologous recombination in the human genome: not all homologous sequences are equal Lupski, James R Genome Biol Minireview Homologous recombination between alleles or non-allelic paralogous sequences does not occur uniformly but is concentrated in 'hotspots' with high recombination rates. Recent studies of these hotspots show that they do not share common sequence motifs, but they do have other features in common. BioMed Central 2004 2004-09-28 /pmc/articles/PMC545587/ /pubmed/15461806 http://dx.doi.org/10.1186/gb-2004-5-10-242 Text en Copyright © 2004 BioMed Central Ltd |
| spellingShingle | Minireview Lupski, James R Hotspots of homologous recombination in the human genome: not all homologous sequences are equal |
| title | Hotspots of homologous recombination in the human genome: not all homologous sequences are equal |
| title_full | Hotspots of homologous recombination in the human genome: not all homologous sequences are equal |
| title_fullStr | Hotspots of homologous recombination in the human genome: not all homologous sequences are equal |
| title_full_unstemmed | Hotspots of homologous recombination in the human genome: not all homologous sequences are equal |
| title_short | Hotspots of homologous recombination in the human genome: not all homologous sequences are equal |
| title_sort | hotspots of homologous recombination in the human genome: not all homologous sequences are equal |
| topic | Minireview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545587/ https://www.ncbi.nlm.nih.gov/pubmed/15461806 http://dx.doi.org/10.1186/gb-2004-5-10-242 |
| work_keys_str_mv | AT lupskijamesr hotspotsofhomologousrecombinationinthehumangenomenotallhomologoussequencesareequal |