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Various meteorological conditions exhibit both immediate and delayed influences on the risk of stroke events: The HEWS–stroke study

We hypothesized that meteorological conditions on the onset day and conditions on the former days may play important roles in the modulation of physical conditions. Associations of meteorological factors and their changes in former days with stroke onset are of interest. We conducted a multicenter r...

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Autores principales: Mukai, Tomoya, Hosomi, Naohisa, Tsunematsu, Miwako, Sueda, Yoshimasa, Shimoe, Yutaka, Ohshita, Tomohiko, Torii, Tsuyoshi, Aoki, Shiro, Nezu, Tomohisa, Maruyama, Hirofumi, Kakehashi, Masayuki, Matsumoto, Masayasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456042/
https://www.ncbi.nlm.nih.gov/pubmed/28575005
http://dx.doi.org/10.1371/journal.pone.0178223
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author Mukai, Tomoya
Hosomi, Naohisa
Tsunematsu, Miwako
Sueda, Yoshimasa
Shimoe, Yutaka
Ohshita, Tomohiko
Torii, Tsuyoshi
Aoki, Shiro
Nezu, Tomohisa
Maruyama, Hirofumi
Kakehashi, Masayuki
Matsumoto, Masayasu
author_facet Mukai, Tomoya
Hosomi, Naohisa
Tsunematsu, Miwako
Sueda, Yoshimasa
Shimoe, Yutaka
Ohshita, Tomohiko
Torii, Tsuyoshi
Aoki, Shiro
Nezu, Tomohisa
Maruyama, Hirofumi
Kakehashi, Masayuki
Matsumoto, Masayasu
author_sort Mukai, Tomoya
collection PubMed
description We hypothesized that meteorological conditions on the onset day and conditions on the former days may play important roles in the modulation of physical conditions. Associations of meteorological factors and their changes in former days with stroke onset are of interest. We conducted a multicenter retrospective study to evaluate the frequency of stroke events and their interaction with meteorological conditions and their daily changes. Acute stroke patients (n = 3935, 73.5±12.4 years, 1610 females) who were admitted to 7 stroke hospitals in three restricted areas were enrolled in this study. Poisson regression models involving time-lag variables was used to compare daily rates of stroke events with mean thermo-hydrological index (THI), atmospheric pressure, and their daily changes. We divided onset days into quintiles based on the THI, atmospheric pressure, and their daily changes for the last 7 days. The frequencies of ischemic stroke significantly increased when THI varied either cooler or warmer from a previous day (extremely cooler, risk ratio (RR) 1.19, 95% confidence interval (CI) 1.05 to 1.34; extremely warmer, RR 1.16, 95% CI 1.03 to 1.31; r(2) = 0.001 for the best regression, p = 0.001). Intracerebral hemorrhage frequencies significantly decreased on high-THI days (extremely high, RR 0.72, 95% CI 0.54 to 0.95; r(2) = 0.013 for the best regression, p<0.001) and increased in high atmospheric pressure days (high, RR 1.31, 95% CI 1.04 to 1.65; r(2) = 0.009 for the best regression, p<0.001). Additionally, even after adjusting for the THI on the onset day and its changes for the other days, intracerebral hemorrhage increased when THI got extremely cooler in 4 days prior (RR 1.33, 95% CI 1.03 to 1.71, r(2) = 0.006 for the best regression, p<0.001). Various meteorological conditions may exhibit influences on stroke onset. And, when temperature cooled, there may be a possibility to show delayed influence on the frequency of intracerebral hemorrhage 4 days later.
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spelling pubmed-54560422017-06-12 Various meteorological conditions exhibit both immediate and delayed influences on the risk of stroke events: The HEWS–stroke study Mukai, Tomoya Hosomi, Naohisa Tsunematsu, Miwako Sueda, Yoshimasa Shimoe, Yutaka Ohshita, Tomohiko Torii, Tsuyoshi Aoki, Shiro Nezu, Tomohisa Maruyama, Hirofumi Kakehashi, Masayuki Matsumoto, Masayasu PLoS One Research Article We hypothesized that meteorological conditions on the onset day and conditions on the former days may play important roles in the modulation of physical conditions. Associations of meteorological factors and their changes in former days with stroke onset are of interest. We conducted a multicenter retrospective study to evaluate the frequency of stroke events and their interaction with meteorological conditions and their daily changes. Acute stroke patients (n = 3935, 73.5±12.4 years, 1610 females) who were admitted to 7 stroke hospitals in three restricted areas were enrolled in this study. Poisson regression models involving time-lag variables was used to compare daily rates of stroke events with mean thermo-hydrological index (THI), atmospheric pressure, and their daily changes. We divided onset days into quintiles based on the THI, atmospheric pressure, and their daily changes for the last 7 days. The frequencies of ischemic stroke significantly increased when THI varied either cooler or warmer from a previous day (extremely cooler, risk ratio (RR) 1.19, 95% confidence interval (CI) 1.05 to 1.34; extremely warmer, RR 1.16, 95% CI 1.03 to 1.31; r(2) = 0.001 for the best regression, p = 0.001). Intracerebral hemorrhage frequencies significantly decreased on high-THI days (extremely high, RR 0.72, 95% CI 0.54 to 0.95; r(2) = 0.013 for the best regression, p<0.001) and increased in high atmospheric pressure days (high, RR 1.31, 95% CI 1.04 to 1.65; r(2) = 0.009 for the best regression, p<0.001). Additionally, even after adjusting for the THI on the onset day and its changes for the other days, intracerebral hemorrhage increased when THI got extremely cooler in 4 days prior (RR 1.33, 95% CI 1.03 to 1.71, r(2) = 0.006 for the best regression, p<0.001). Various meteorological conditions may exhibit influences on stroke onset. And, when temperature cooled, there may be a possibility to show delayed influence on the frequency of intracerebral hemorrhage 4 days later. Public Library of Science 2017-06-02 /pmc/articles/PMC5456042/ /pubmed/28575005 http://dx.doi.org/10.1371/journal.pone.0178223 Text en © 2017 Mukai et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Mukai, Tomoya
Hosomi, Naohisa
Tsunematsu, Miwako
Sueda, Yoshimasa
Shimoe, Yutaka
Ohshita, Tomohiko
Torii, Tsuyoshi
Aoki, Shiro
Nezu, Tomohisa
Maruyama, Hirofumi
Kakehashi, Masayuki
Matsumoto, Masayasu
Various meteorological conditions exhibit both immediate and delayed influences on the risk of stroke events: The HEWS–stroke study
title Various meteorological conditions exhibit both immediate and delayed influences on the risk of stroke events: The HEWS–stroke study
title_full Various meteorological conditions exhibit both immediate and delayed influences on the risk of stroke events: The HEWS–stroke study
title_fullStr Various meteorological conditions exhibit both immediate and delayed influences on the risk of stroke events: The HEWS–stroke study
title_full_unstemmed Various meteorological conditions exhibit both immediate and delayed influences on the risk of stroke events: The HEWS–stroke study
title_short Various meteorological conditions exhibit both immediate and delayed influences on the risk of stroke events: The HEWS–stroke study
title_sort various meteorological conditions exhibit both immediate and delayed influences on the risk of stroke events: the hews–stroke study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456042/
https://www.ncbi.nlm.nih.gov/pubmed/28575005
http://dx.doi.org/10.1371/journal.pone.0178223
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