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FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25

The neurodegenerative disease glaucoma is one of the leading causes of blindness in the world. Glaucoma is characterized by progressive visual field loss caused by retinal ganglion cell (RGC) death. Both surgical glaucoma treatments and medications are available, however, they only halt glaucoma pro...

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Detalles Bibliográficos
Autores principales: Rasnitsyn, Alexandra, Doucette, Lance, Seifi, Morteza, Footz, Tim, Raymond, Vincent, Walter, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456087/
https://www.ncbi.nlm.nih.gov/pubmed/28575017
http://dx.doi.org/10.1371/journal.pone.0178518