Prader-Willi Syndrome: The Disease that Opened up Epigenomic-Based Preemptive Medicine

Prader-Willi syndrome (PWS) is a congenital neurodevelopmental disorder caused by loss of function of paternally expressed genes on chromosome 15 due to paternal deletion of 15q11–q13, maternal uniparental disomy for chromosome 15, or an imprinting mutation. We previously developed a DNA methylation...

Descripción completa

Detalles Bibliográficos
Autores principales: Kubota, Takeo, Miyake, Kunio, Hariya, Natsuyo, Tran Nguyen Quoc, Vuong, Mochizuki, Kazuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456307/
https://www.ncbi.nlm.nih.gov/pubmed/28933395
http://dx.doi.org/10.3390/diseases4010015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456307/
https://www.ncbi.nlm.nih.gov/pubmed/28933395
http://dx.doi.org/10.3390/diseases4010015

Ejemplares similares