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The role of reactive oxygen intermediates in the intracellular fate of Leptospira interrogans in the macrophages of different hosts

BACKGROUND: Pathogenic species of Leptospira cause leptospirosis, a global zoonotic disease. Our previous work showed that leptospires survive and replicate in human macrophages but are killed in murine macrophages. However, the mechanism responsible for the different intracellular fates of leptospi...

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Detalles Bibliográficos
Autores principales: Li, Shijun, Li, Peili, Zhang, Lei, Hu, Weilin, Wang, Ming, Liu, Ying, Tang, Guangpeng, Wang, Dingming, Zhou, Bijun, Yan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456347/
https://www.ncbi.nlm.nih.gov/pubmed/28575082
http://dx.doi.org/10.1371/journal.pone.0178618