Cargando…

Immunization of a wild koala population with a recombinant Chlamydia pecorum Major Outer Membrane Protein (MOMP) or Polymorphic Membrane Protein (PMP) based vaccine: New insights into immune response, protection and clearance

We assessed the effects of two different single-dose anti-Chlamydia pecorum (C. pecorum) vaccines (containing either Major Outer Membrane Protein (3MOMP) or Polymorphic Membrane Protein (Pmp) as antigens) on the immune response of a group of wild koalas. Both vaccines elicited a systemic humoral res...

Descripción completa

Detalles Bibliográficos
Autores principales:	Desclozeaux, Marion, Robbins, Amy, Jelocnik, Martina, Khan, Shahneaz Ali, Hanger, Jon, Gerdts, Volker, Potter, Andrew, Polkinghorne, Adam, Timms, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456371/ https://www.ncbi.nlm.nih.gov/pubmed/28575080 http://dx.doi.org/10.1371/journal.pone.0178786

Ejemplares similares

Antibody and Cytokine Responses of Koalas (Phascolarctos cinereus) Vaccinated with Recombinant Chlamydial Major Outer Membrane Protein (MOMP) with Two Different Adjuvants
por: Khan, Shahneaz Ali, et al.
Publicado: (2016)

Chlamydia pecorum gastrointestinal tract infection associations with urogenital tract infections in the koala (Phascolarctos cinereus)
por: Phillips, Samuel, et al.
Publicado: (2018)

Vaccination of koalas (Phascolarctos cinereus) against Chlamydia pecorum using synthetic peptides derived from the major outer membrane protein
por: Nyari, Sharon, et al.
Publicado: (2018)

Comparative genomics of koala, cattle and sheep strains of Chlamydia pecorum
por: Bachmann, Nathan L, et al.
Publicado: (2014)

A Prototype Recombinant-Protein Based Chlamydia pecorum Vaccine Results in Reduced Chlamydial Burden and Less Clinical Disease in Free-Ranging Koalas (Phascolarctos cinereus)
por: Waugh, Courtney, et al.
Publicado: (2016)

Molecular and serological dynamics of Chlamydia pecorum infection in a longitudinal study of prime lamb production
por: Bommana, Sankhya, et al.
Publicado: (2018)

Humoral immune response against two surface antigens of Chlamydia pecorum in vaccinated and naturally infected sheep
por: Bommana, Sankhya, et al.
Publicado: (2017)

Novel molecular markers of Chlamydia pecorum genetic diversity in the koala (Phascolarctos cinereus)
por: Marsh, James, et al.
Publicado: (2011)

Vaccination of Koalas with a Recombinant Chlamydia pecorum Major Outer Membrane Protein Induces Antibodies of Different Specificity Compared to Those Following a Natural Live Infection
por: Kollipara, Avinash, et al.
Publicado: (2013)

Reduction of Chlamydia pecorum and Koala Retrovirus subtype B expression in wild koalas vaccinated with novel peptide and peptide/recombinant protein formulations
por: Quigley, Bonnie L, et al.
Publicado: (2023)

Therapeutic effect of a Chlamydia pecorum recombinant major outer membrane protein vaccine on ocular disease in koalas (Phascolarctos cinereus)
por: Nyari, Sharon, et al.
Publicado: (2019)

Molecular characterisation of the Chlamydia pecorum plasmid from porcine, ovine, bovine, and koala strains indicates plasmid-strain co-evolution
por: Jelocnik, Martina, et al.
Publicado: (2016)

Efficacy of a synthetic peptide Chlamydia pecorum major outer membrane protein vaccine in a wild koala (Phascolarctos cinereus) population
por: Simpson, Sarah J., et al.
Publicado: (2023)

Preliminary Characterisation of Tumor Necrosis Factor Alpha and Interleukin-10 Responses to Chlamydia pecorum Infection in the Koala (Phascolarctos cinereus)
por: Mathew, Marina, et al.
Publicado: (2013)

Genetic diversity in the plasticity zone and the presence of the chlamydial plasmid differentiates Chlamydia pecorum strains from pigs, sheep, cattle, and koalas
por: Jelocnik, Martina, et al.
Publicado: (2015)

Chlamydia pecorum prevalence in South Australian koala (Phascolarctos cinereus) populations: Identification and modelling of a population free from infection
por: Fabijan, Jessica, et al.
Publicado: (2019)

Identification, characterisation and expression analysis of natural killer receptor genes in Chlamydia pecorum infected koalas (Phascolarctos cinereus)
por: Morris, Katrina M., et al.
Publicado: (2015)

Koala immunogenetics and chlamydial strain type are more directly involved in chlamydial disease progression in koalas from two south east Queensland koala populations than koala retrovirus subtypes
por: Robbins, Amy, et al.
Publicado: (2020)

Molecular and pathological insights into Chlamydia pecorum-associated sporadic bovine encephalomyelitis (SBE) in Western Australia
por: Jelocnik, Martina, et al.
Publicado: (2014)

Is Chlamydia to Blame for Koala Reproductive Cysts?
por: Phillips, Samuel, et al.
Publicado: (2021)

Molecular evidence of Chlamydia pecorum and arthropod-associated Chlamydiae in an expanded range of marsupials
por: Burnard, Delaney, et al.
Publicado: (2017)

Vaccination of koalas during antibiotic treatment for Chlamydia-induced cystitis induces an improved antibody response to Chlamydia pecorum
por: Phillips, Samuel, et al.
Publicado: (2020)

Clinical, diagnostic and pathologic features of presumptive cases of Chlamydia pecorum-associated arthritis in Australian sheep flocks
por: Walker, Evelyn, et al.
Publicado: (2016)

Completing the Genome Sequence of Chlamydia pecorum Strains MC/MarsBar and DBDeUG: New Insights into This Enigmatic Koala (Phascolarctos cinereus) Pathogen
por: White, Rhys T., et al.
Publicado: (2021)

A retrospective study on antibacterial treatments for koalas infected with Chlamydia pecorum
por: Chen, Chien-Jung, et al.
Publicado: (2023)

Development and evaluation of rapid novel isothermal amplification assays for important veterinary pathogens: Chlamydia psittaci and Chlamydia pecorum
por: Jelocnik, Martina, et al.
Publicado: (2017)

Longitudinal study of wild koalas (Phascolarctos cinereus) reveals chlamydial disease progression in two thirds of infected animals
por: Robbins, Amy, et al.
Publicado: (2019)

Koala cathelicidin PhciCath5 has antimicrobial activity, including against Chlamydia pecorum
por: Peel, Emma, et al.
Publicado: (2021)

Microbiota composition of the koala (Phascolarctos cinereus) ocular and urogenital sites, and their association with Chlamydia infection and disease
por: Vidgen, Miranda E., et al.
Publicado: (2017)

Bioinformatic Analysis of Chlamydia trachomatis Polymorphic Membrane Proteins PmpE, PmpF, PmpG and PmpH as Potential Vaccine Antigens
por: Nunes, Alexandra, et al.
Publicado: (2015)

Overexpression of the Bam Complex Improves the Production of Chlamydia trachomatis MOMP in the E. coli Outer Membrane
por: Huynh, Dung T., et al.
Publicado: (2022)

Analysis of Polymorphic Membrane Protein Expression in Cultured Cells Identifies PmpA and PmpH of Chlamydia psittaci as Candidate Factors in Pathogenesis and Immunity to Infection
por: Van Lent, Sarah, et al.
Publicado: (2016)

Chlamydia pecorum detection in aborted and stillborn lambs from Western Australia
por: Clune, Tom, et al.
Publicado: (2021)

Evaluation of a biosecurity survey approach for contamination by Chlamydia pecorum in koala rehabilitation, field capture, and captive settings
por: Casteriano, Andrea, et al.
Publicado: (2023)

Chlamydia Serine Protease Inhibitor, targeting HtrA, as a New Treatment for Koala Chlamydia infection
por: Lawrence, Amba, et al.
Publicado: (2016)

Helping koalas battle disease – Recent advances in Chlamydia and koala retrovirus (KoRV) disease understanding and treatment in koalas
por: Quigley, Bonnie L, et al.
Publicado: (2020)

Chlamydia pecorum Ovine Abortion: Associations between Maternal Infection and Perinatal Mortality
por: Jenkins, Cheryl, et al.
Publicado: (2021)

Comparison of clinical performance of antigen based-enzyme immunoassay (EIA) and major outer membrane protein (MOMP)-PCR for detection of genital Chlamydia trachomatis infection
por: Nateghi Rostami, Mahmoud, et al.
Publicado: (2016)

Complement component C3 fixes selectively to the major outer membrane protein (MOMP) of Legionella pneumophila and mediates phagocytosis of liposome-MOMP complexes by human monocytes
Publicado: (1990)

Optimising the short and long-term clinical outcomes for koalas (Phascolarctos cinereus) during treatment for chlamydial infection and disease
por: Robbins, Amy, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_d52r9bju98ercdav3m5tqeiism