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Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats

BACKGROUND: Cystatin C, a marker of kidney injury, is freely filtered in the glomeruli and reabsorbed by the proximal tubules. Megalin and cubilin are endocytic receptors essential for reabsorption of most filtered proteins. This study examines the role of these receptors for the uptake and excretio...

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Detalles Bibliográficos
Autores principales:	Jensen, Danny, Kierulf-Lassen, Casper, Kristensen, Marie Louise Vindvad, Nørregaard, Rikke, Weyer, Kathrin, Nielsen, Rikke, Christensen, Erik Ilsø, Birn, Henrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456377/ https://www.ncbi.nlm.nih.gov/pubmed/28575050 http://dx.doi.org/10.1371/journal.pone.0178796

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