Cargando…
Antifungal Tc17 cells are durable and stable, persisting as long-lasting vaccine memory without plasticity towards IFNγ cells
Our understanding of persistence and plasticity of IL-17A(+) memory T cells is clouded by conflicting results in models analyzing T helper 17 cells. We studied memory IL-17A(+) CD8(+) T-cell (Tc17) homeostasis, persistence and plasticity during fungal vaccine immunity. We report that vaccine-induced...
Autores principales: | Nanjappa, Som Gowda, McDermott, Andrew J., Fites, J. Scott, Galles, Kevin, Wüthrich, Marcel, Deepe, George S., Klein, Bruce S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456400/ https://www.ncbi.nlm.nih.gov/pubmed/28542595 http://dx.doi.org/10.1371/journal.ppat.1006356 |
Ejemplares similares
-
Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia
por: Nanjappa, Som Gowda, et al.
Publicado: (2015) -
Tc17 Cells Mediate Vaccine Immunity against Lethal Fungal Pneumonia in Immune Deficient Hosts Lacking CD4(+) T Cells
por: Nanjappa, Som Gowda, et al.
Publicado: (2012) -
GM-CSF(+) Tc17 cells are required to bolster vaccine immunity against lethal fungal pneumonia without causing overt pathology
por: Mudalagiriyappa, Srinivasu, et al.
Publicado: (2022) -
Structure and Function of a Fungal Adhesin that Binds Heparin and Mimics Thrombospondin-1 by Blocking T Cell Activation and Effector Function
por: Brandhorst, T. Tristan, et al.
Publicado: (2013) -
T cell responses to control fungal infection in an immunological memory lens
por: Sharma, Jaishree, et al.
Publicado: (2022)