Curcumin and Osteosarcoma: Can Invertible Polymeric Micelles Help?

Systematic review of experimental and clinical data on the use of curcumin in the treatment of osteosarcoma is presented. The current status of curcumin’s therapeutic potential against bone cancer is analyzed in regard to using polymeric micelles (including recently developed invertible, responsive,...

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Autores principales: Maran, Avudaiappan, Yaszemski, Michael J., Kohut, Ananiy, Voronov, Andriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456898/
https://www.ncbi.nlm.nih.gov/pubmed/28773642
http://dx.doi.org/10.3390/ma9070520
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author Maran, Avudaiappan
Yaszemski, Michael J.
Kohut, Ananiy
Voronov, Andriy
author_facet Maran, Avudaiappan
Yaszemski, Michael J.
Kohut, Ananiy
Voronov, Andriy
author_sort Maran, Avudaiappan
collection PubMed
description Systematic review of experimental and clinical data on the use of curcumin in the treatment of osteosarcoma is presented. The current status of curcumin’s therapeutic potential against bone cancer is analyzed in regard to using polymeric micelles (including recently developed invertible, responsive, micelles) as a platform for curcumin delivery to treat osteosarcoma. The potential of micellar assemblies from responsive macromolecules in a controlled delivery of curcumin to osteosarcoma cells, and the release using a new inversion mechanism is revealed.
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spelling pubmed-54568982017-07-28 Curcumin and Osteosarcoma: Can Invertible Polymeric Micelles Help? Maran, Avudaiappan Yaszemski, Michael J. Kohut, Ananiy Voronov, Andriy Materials (Basel) Review Systematic review of experimental and clinical data on the use of curcumin in the treatment of osteosarcoma is presented. The current status of curcumin’s therapeutic potential against bone cancer is analyzed in regard to using polymeric micelles (including recently developed invertible, responsive, micelles) as a platform for curcumin delivery to treat osteosarcoma. The potential of micellar assemblies from responsive macromolecules in a controlled delivery of curcumin to osteosarcoma cells, and the release using a new inversion mechanism is revealed. MDPI 2016-06-27 /pmc/articles/PMC5456898/ /pubmed/28773642 http://dx.doi.org/10.3390/ma9070520 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Maran, Avudaiappan
Yaszemski, Michael J.
Kohut, Ananiy
Voronov, Andriy
Curcumin and Osteosarcoma: Can Invertible Polymeric Micelles Help?
title Curcumin and Osteosarcoma: Can Invertible Polymeric Micelles Help?
title_full Curcumin and Osteosarcoma: Can Invertible Polymeric Micelles Help?
title_fullStr Curcumin and Osteosarcoma: Can Invertible Polymeric Micelles Help?
title_full_unstemmed Curcumin and Osteosarcoma: Can Invertible Polymeric Micelles Help?
title_short Curcumin and Osteosarcoma: Can Invertible Polymeric Micelles Help?
title_sort curcumin and osteosarcoma: can invertible polymeric micelles help?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456898/
https://www.ncbi.nlm.nih.gov/pubmed/28773642
http://dx.doi.org/10.3390/ma9070520
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AT kohutananiy curcuminandosteosarcomacaninvertiblepolymericmicelleshelp
AT voronovandriy curcuminandosteosarcomacaninvertiblepolymericmicelleshelp

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