RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases

For transcription through chromatin, RNA polymerase (Pol) II associates with elongation factors (EFs). Here we show that many EFs crosslink to RNA emerging from transcribing Pol II in the yeast Saccharomyces cerevisiae. Most EFs crosslink preferentially to mRNAs, rather than unstable non-coding RNAs...

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Detalles Bibliográficos
Autores principales: Battaglia, Sofia, Lidschreiber, Michael, Baejen, Carlo, Torkler, Phillipp, Vos, Seychelle M, Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457138/
https://www.ncbi.nlm.nih.gov/pubmed/28537551
http://dx.doi.org/10.7554/eLife.25637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457138/
https://www.ncbi.nlm.nih.gov/pubmed/28537551
http://dx.doi.org/10.7554/eLife.25637

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