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miR-148a-mediated estrogen-induced cholestasis in intrahepatic cholestasis of pregnancy: Role of PXR/MRP3
Intrahepatic cholestasis of pregnancy (ICP) is an idiopathic liver disease while the biochemical characteristic is the elevated level of total bile acid (TBA). The present study investigated whether miR-148a mediates the induced effect of estrogen on the development of ICP and the proper mechanism:...
Autores principales: | Rao, Zhou-Zhou, Zhang, Xiao-Wen, Ding, Yi-Ling, Yang, Meng-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457162/ https://www.ncbi.nlm.nih.gov/pubmed/28575098 http://dx.doi.org/10.1371/journal.pone.0178702 |
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