An Intriguing Method for Fabricating Arbitrarily Shaped “Matreshka” Hydrogels Using a Self-Healing Template

This work describes an intriguing strategy for the creation of arbitrarily shaped hydrogels utilizing a self-healing template (SHT). A SHT was loaded with a photo-crosslinkable monomer, PEG diacrylate (PEGDA), and then ultraviolet light (UV) crosslinked after first shaping. The SHT template was remo...

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Detalles Bibliográficos
Autores principales: Sato, Takeshi, Uto, Koichiro, Aoyagi, Takao, Ebara, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457250/
https://www.ncbi.nlm.nih.gov/pubmed/28773983
http://dx.doi.org/10.3390/ma9110864
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author Sato, Takeshi
Uto, Koichiro
Aoyagi, Takao
Ebara, Mitsuhiro
author_facet Sato, Takeshi
Uto, Koichiro
Aoyagi, Takao
Ebara, Mitsuhiro
author_sort Sato, Takeshi
collection PubMed
description This work describes an intriguing strategy for the creation of arbitrarily shaped hydrogels utilizing a self-healing template (SHT). A SHT was loaded with a photo-crosslinkable monomer, PEG diacrylate (PEGDA), and then ultraviolet light (UV) crosslinked after first shaping. The SHT template was removed by simple washing with water, leaving behind the hydrogel in the desired physical shape. A hierarchical 3D structure such as “Matreshka” boxes were successfully prepared by simply repeating the “self-healing” and “photo-irradiation” processes. We have also explored the potential of the SHT system for the manipulation of cells.
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spelling pubmed-54572502017-07-28 An Intriguing Method for Fabricating Arbitrarily Shaped “Matreshka” Hydrogels Using a Self-Healing Template Sato, Takeshi Uto, Koichiro Aoyagi, Takao Ebara, Mitsuhiro Materials (Basel) Communication This work describes an intriguing strategy for the creation of arbitrarily shaped hydrogels utilizing a self-healing template (SHT). A SHT was loaded with a photo-crosslinkable monomer, PEG diacrylate (PEGDA), and then ultraviolet light (UV) crosslinked after first shaping. The SHT template was removed by simple washing with water, leaving behind the hydrogel in the desired physical shape. A hierarchical 3D structure such as “Matreshka” boxes were successfully prepared by simply repeating the “self-healing” and “photo-irradiation” processes. We have also explored the potential of the SHT system for the manipulation of cells. MDPI 2016-10-25 /pmc/articles/PMC5457250/ /pubmed/28773983 http://dx.doi.org/10.3390/ma9110864 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Sato, Takeshi
Uto, Koichiro
Aoyagi, Takao
Ebara, Mitsuhiro
An Intriguing Method for Fabricating Arbitrarily Shaped “Matreshka” Hydrogels Using a Self-Healing Template
title An Intriguing Method for Fabricating Arbitrarily Shaped “Matreshka” Hydrogels Using a Self-Healing Template
title_full An Intriguing Method for Fabricating Arbitrarily Shaped “Matreshka” Hydrogels Using a Self-Healing Template
title_fullStr An Intriguing Method for Fabricating Arbitrarily Shaped “Matreshka” Hydrogels Using a Self-Healing Template
title_full_unstemmed An Intriguing Method for Fabricating Arbitrarily Shaped “Matreshka” Hydrogels Using a Self-Healing Template
title_short An Intriguing Method for Fabricating Arbitrarily Shaped “Matreshka” Hydrogels Using a Self-Healing Template
title_sort intriguing method for fabricating arbitrarily shaped “matreshka” hydrogels using a self-healing template
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457250/
https://www.ncbi.nlm.nih.gov/pubmed/28773983
http://dx.doi.org/10.3390/ma9110864
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