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Synthesis of Reabsorption-Suppressed Type-II/Type-I ZnSe/CdS/ZnS Core/Shell Quantum Dots and Their Application for Immunosorbent Assay

We report a phosphine-free one-pot method to synthesize ZnSe/CdS/ZnS core-shell quantum dots (QDs) with composite type-II/type-I structures and consequent reabsorption suppression properties. The as-synthesized QDs possess high efficient red emission (with quantum yield of 82%) and high optical stab...

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Detalles Bibliográficos
Autores principales: Wang, Sheng, Li, Jin Jie, Lv, Yanbing, Wu, Ruili, Xing, Ming, Shen, Huaibin, Wang, Hongzhe, Li, Lin Song, Chen, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457375/
https://www.ncbi.nlm.nih.gov/pubmed/28582961
http://dx.doi.org/10.1186/s11671-017-2135-4
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author Wang, Sheng
Li, Jin Jie
Lv, Yanbing
Wu, Ruili
Xing, Ming
Shen, Huaibin
Wang, Hongzhe
Li, Lin Song
Chen, Xia
author_facet Wang, Sheng
Li, Jin Jie
Lv, Yanbing
Wu, Ruili
Xing, Ming
Shen, Huaibin
Wang, Hongzhe
Li, Lin Song
Chen, Xia
author_sort Wang, Sheng
collection PubMed
description We report a phosphine-free one-pot method to synthesize ZnSe/CdS/ZnS core-shell quantum dots (QDs) with composite type-II/type-I structures and consequent reabsorption suppression properties. The as-synthesized QDs possess high efficient red emission (with quantum yield of 82%) and high optical stability. Compared to type-I QDs, the ZnSe/CdS/ZnS QDs show larger Stokes shift and lower reabsorption which can reduce the emission loss and improve the level of fluorescence output. The ZnSe/CdS/ZnS QDs are used as fluorescent labels to exploit their application in fluorescence-linked immunosorbent assay (FLISA) for the first time in the detection of C-reactive protein (CRP) with a limit of detection (LOD) of 0.85 ng/mL, which is more sensitive than that of CdSe/ZnS type-I QDs based FLISA (1.00 ng/mL). The results indicate that the ZnSe/CdS/ZnS type-II/type-I QDs may be good candidates for applications in biomedical information detection. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s11671-017-2135-4) contains supplementary material, which is available to authorized users.
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spelling pubmed-54573752017-06-16 Synthesis of Reabsorption-Suppressed Type-II/Type-I ZnSe/CdS/ZnS Core/Shell Quantum Dots and Their Application for Immunosorbent Assay Wang, Sheng Li, Jin Jie Lv, Yanbing Wu, Ruili Xing, Ming Shen, Huaibin Wang, Hongzhe Li, Lin Song Chen, Xia Nanoscale Res Lett Nano Express We report a phosphine-free one-pot method to synthesize ZnSe/CdS/ZnS core-shell quantum dots (QDs) with composite type-II/type-I structures and consequent reabsorption suppression properties. The as-synthesized QDs possess high efficient red emission (with quantum yield of 82%) and high optical stability. Compared to type-I QDs, the ZnSe/CdS/ZnS QDs show larger Stokes shift and lower reabsorption which can reduce the emission loss and improve the level of fluorescence output. The ZnSe/CdS/ZnS QDs are used as fluorescent labels to exploit their application in fluorescence-linked immunosorbent assay (FLISA) for the first time in the detection of C-reactive protein (CRP) with a limit of detection (LOD) of 0.85 ng/mL, which is more sensitive than that of CdSe/ZnS type-I QDs based FLISA (1.00 ng/mL). The results indicate that the ZnSe/CdS/ZnS type-II/type-I QDs may be good candidates for applications in biomedical information detection. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s11671-017-2135-4) contains supplementary material, which is available to authorized users. Springer US 2017-06-02 /pmc/articles/PMC5457375/ /pubmed/28582961 http://dx.doi.org/10.1186/s11671-017-2135-4 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Nano Express
Wang, Sheng
Li, Jin Jie
Lv, Yanbing
Wu, Ruili
Xing, Ming
Shen, Huaibin
Wang, Hongzhe
Li, Lin Song
Chen, Xia
Synthesis of Reabsorption-Suppressed Type-II/Type-I ZnSe/CdS/ZnS Core/Shell Quantum Dots and Their Application for Immunosorbent Assay
title Synthesis of Reabsorption-Suppressed Type-II/Type-I ZnSe/CdS/ZnS Core/Shell Quantum Dots and Their Application for Immunosorbent Assay
title_full Synthesis of Reabsorption-Suppressed Type-II/Type-I ZnSe/CdS/ZnS Core/Shell Quantum Dots and Their Application for Immunosorbent Assay
title_fullStr Synthesis of Reabsorption-Suppressed Type-II/Type-I ZnSe/CdS/ZnS Core/Shell Quantum Dots and Their Application for Immunosorbent Assay
title_full_unstemmed Synthesis of Reabsorption-Suppressed Type-II/Type-I ZnSe/CdS/ZnS Core/Shell Quantum Dots and Their Application for Immunosorbent Assay
title_short Synthesis of Reabsorption-Suppressed Type-II/Type-I ZnSe/CdS/ZnS Core/Shell Quantum Dots and Their Application for Immunosorbent Assay
title_sort synthesis of reabsorption-suppressed type-ii/type-i znse/cds/zns core/shell quantum dots and their application for immunosorbent assay
topic Nano Express
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457375/
https://www.ncbi.nlm.nih.gov/pubmed/28582961
http://dx.doi.org/10.1186/s11671-017-2135-4
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