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A novel anti-CD22 scFv–apoptin fusion protein induces apoptosis in malignant B-cells
CD22 marker is a highly internalizing antigen which is located on the surface of B-cells and is being used as a promising target for treatment of B cell malignancies. Monoclonal antibodies targeting CD22 have been introduced and some are currently under investigation in clinical trials. Building on...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457376/ https://www.ncbi.nlm.nih.gov/pubmed/28582973 http://dx.doi.org/10.1186/s13568-017-0410-5 |