Aminophylline restores glucocorticoid sensitivity in a guinea pig model of sudden sensorineural hearing loss induced by lipopolysaccharide

Glucocorticoids have been used to treat hearing loss and vestibular dysfunction for many years. However, some reports have indicated that a subset of patients with these disorders exhibit glucocorticoid insensitivity or resistance. A reduction in histone deacetylase 2 (HDAC2) activity and expression...

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Detalles Bibliográficos
Autores principales: Zhou, Qiong-Qiong, Dai, Yan-Hong, Du, Xiao-Ping, Hou, Jie, Qi, Hui, She, Wan-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457401/
https://www.ncbi.nlm.nih.gov/pubmed/28578424
http://dx.doi.org/10.1038/s41598-017-02956-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457401/
https://www.ncbi.nlm.nih.gov/pubmed/28578424
http://dx.doi.org/10.1038/s41598-017-02956-x

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