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Resveratrol Pretreatment Attenuates Concanavalin A-induced Hepatitis through Reverse of Aberration in the Immune Response and Regenerative Capacity in Aged Mice

Loss of regenerative capacity plays a critical role in age-related autoimmune hepatitis. Evidence implicates SIRT1 and p66(shc) in cell senescence, apoptosis, oxidative stress, and proliferation. This study investigated the effect of resveratrol on concanavalin A (Con A)-induced hepatitis in aged mi...

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Detalles Bibliográficos
Autores principales: Huang, Tse-Hung, Chen, Chin-Chang, Liu, Hsuan-Miao, Lee, Tzung-Yan, Shieh, Sue-Heui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457448/
https://www.ncbi.nlm.nih.gov/pubmed/28578410
http://dx.doi.org/10.1038/s41598-017-02881-z