Cargando…

Structural basis for perception of diverse chemical substances by T1r taste receptors

The taste receptor type 1 (T1r) family perceives ‘palatable' tastes. These receptors function as T1r2-T1r3 and T1r1-T1r3 heterodimers to recognize a wide array of sweet and umami (savory) tastes in sugars and amino acids. Nonetheless, it is unclear how diverse tastes are recognized by so few re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nuemket, Nipawan, Yasui, Norihisa, Kusakabe, Yuko, Nomura, Yukiyo, Atsumi, Nanako, Akiyama, Shuji, Nango, Eriko, Kato, Yukinari, Kaneko, Mika K., Takagi, Junichi, Hosotani, Maiko, Yamashita, Atsuko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457512/ https://www.ncbi.nlm.nih.gov/pubmed/28534491 http://dx.doi.org/10.1038/ncomms15530

Ejemplares similares

Taste substance binding elicits conformational change of taste receptor T1r heterodimer extracellular domains
por: Nango, Eriko, et al.
Publicado: (2016)

Chloride ions evoke taste sensations by binding to the extracellular ligand-binding domain of sweet/umami taste receptors
por: Atsumi, Nanako, et al.
Publicado: (2023)

Differential scanning fluorimetric analysis of the amino-acid binding to taste receptor using a model receptor protein, the ligand-binding domain of fish T1r2a/T1r3
por: Yoshida, Takashi, et al.
Publicado: (2019)

Distinct Human and Mouse Membrane Trafficking Systems for Sweet Taste Receptors T1r2 and T1r3
por: Shimizu, Madoka, et al.
Publicado: (2014)

Taste of breath: the temporal order of taste and smell synchronized with breathing as a determinant for taste and olfactory integration
por: Kakutani, Yuya, et al.
Publicado: (2017)

Crystallization and X-ray analysis of 23 nm virus-like particles from Norovirus Chiba strain
por: Hasegawa, Kazuya, et al.
Publicado: (2017)

Site-specific epitope insertion into recombinant proteins using the MAP tag system
por: Wakasa, Ayami, et al.
Publicado: (2020)

Quantification of the Flavor and Taste of Gonads from the Sea Urchin Mesocentrotus nudus Using GC–MS and a Taste-Sensing System
por: Takagi, Satomi, et al.
Publicado: (2020)

Development of a dose-limiting data collection strategy for serial synchrotron rotation crystallography
por: Hasegawa, Kazuya, et al.
Publicado: (2017)

Investigating the Effect of Substituting a Single Cysteine Residue on the Thermal Stability of an Engineered Sweet Protein, Single-Chain Monellin
por: Ohnuma, Kyosuke, et al.
Publicado: (2023)

Specific modification at the C-terminal lysine residue of the green fluorescent protein variant, GFPuv, expressed in Escherichia coli
por: Nakatani, Takahiro, et al.
Publicado: (2019)

Structural basis for ligand capture and release by the endocytic receptor ApoER2
por: Hirai, Hidenori, et al.
Publicado: (2017)

Structural Basis for Variant-Specific Neuroligin-Binding by α-Neurexin
por: Tanaka, Hiroki, et al.
Publicado: (2011)

Relationships between the response of the sweet taste receptor, salivation toward sweeteners, and sweetness intensity
por: Kusakabe, Yuko, et al.
Publicado: (2020)

Probing conformational and functional states of human hepatocyte growth factor by a panel of monoclonal antibodies
por: Umitsu, Masataka, et al.
Publicado: (2016)

Characterization of Monoclonal Antibody LpMab-3 Recognizing Sialylated Glycopeptide of Podoplanin
por: Oki, Hiroharu, et al.
Publicado: (2015)

A Cancer-specific Monoclonal Antibody Recognizes the Aberrantly Glycosylated Podoplanin
por: Kato, Yukinari, et al.
Publicado: (2014)

Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism
por: Fadini, Alisia, et al.
Publicado: (2023)

Explicit and Implicit Responses to Tasting Drinks Associated with Different Tasting Experiences
por: Kaneko, Daisuke, et al.
Publicado: (2019)

MAP Tag: A Novel Tagging System for Protein Purification and Detection
por: Fujii, Yuki, et al.
Publicado: (2016)

Establishment of C(20)Mab-11, a novel anti-CD20 monoclonal antibody, for the detection of B cells
por: Furusawa, Yoshikazu, et al.
Publicado: (2020)

RIEDL tag: A novel pentapeptide tagging system for transmembrane protein purification
por: Asano, Teizo, et al.
Publicado: (2020)

Development and characterization of TrMab-6, a novel anti-TROP2 monoclonal antibody for antigen detection in breast cancer
por: Sayama, Yusuke, et al.
Publicado: (2021)

Roles of Podoplanin in Malignant Progression of Tumor
por: Suzuki, Hiroyuki, et al.
Publicado: (2022)

Children’s Perceived Competence Scale: reevaluation in a population of Japanese elementary and junior high school students
por: Nagai, Yukiyo, et al.
Publicado: (2018)

Bitter Taste Sensitivity and the Expression of Bitter Taste Receptors at Different Growth Stages of Chicks
por: Dey, Bapon, et al.
Publicado: (2018)

Detection of high PD-L1 expression in oral cancers by a novel monoclonal antibody L(1)Mab-4
por: Yamada, Shinji, et al.
Publicado: (2018)

Determination of critical epitope of PcMab-47 against human podocalyxin
por: Itai, Shunsuke, et al.
Publicado: (2018)

A cancer-specific anti-podocalyxin monoclonal antibody (60-mG(2a)-f) exerts antitumor effects in mouse xenograft models of pancreatic carcinoma
por: Kaneko, Mika K., et al.
Publicado: (2020)

Epitope mapping of an anti-diacylglycerol kinase delta monoclonal antibody DdMab-1
por: Sano, Masato, et al.
Publicado: (2020)

Establishment and Epitope Mapping of Anti-Diacylglycerol Kinase α Monoclonal Antibody DaMab-8 for Immunohistochemical Analyses
por: Sano, Masato, et al.
Publicado: (2020)

Epitope Analysis of an Anti-Whale Podoplanin Monoclonal Antibody, PMab-237, Using Flow Cytometry
por: Sayama, Yusuke, et al.
Publicado: (2020)

A Humanized and Defucosylated Antibody against Podoplanin (humLpMab-23-f) Exerts Antitumor Activities in Human Lung Cancer and Glioblastoma Xenograft Models
por: Suzuki, Hiroyuki, et al.
Publicado: (2023)

Establishment of a Novel Anti-CD44 Variant 10 Monoclonal Antibody C(44)Mab-18 for Immunohistochemical Analysis against Oral Squamous Cell Carcinomas
por: Ishikawa, Kenichiro, et al.
Publicado: (2023)

Isocitrate dehydrogenase 2 mutation is a frequent event in osteosarcoma detected by a multi-specific monoclonal antibody MsMab-1
por: Liu, Xing, et al.
Publicado: (2013)

Taste Receptors beyond Taste Buds
por: Ki, Su Young, et al.
Publicado: (2022)

Pathogenesis of taste impairment and salivary dysfunction in COVID-19 patients
por: Okada, Yasuo, et al.
Publicado: (2021)

Immunohistochemical Examination of Novel Rat Monoclonal Antibodies against Mouse and Human Podoplanin
por: Kaji, Chiaki, et al.
Publicado: (2012)

Epitope mapping of anti-mouse podoplanin monoclonal antibody PMab-1
por: Yamada, Shinji, et al.
Publicado: (2018)

RAP Tag and PMab-2 Antibody: A Tagging System for Detecting and Purifying Proteins in Plant Cells
por: Miura, Kenji, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_sdi1l1c4a6rid554p7lmjn96f3