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An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides
A method for selective and comprehensive enrichment of N-linked glycopeptides was developed to facilitate detection of micro-heterogeneity of N-glycosylation. The method takes advantage of the inherent properties of Fbs1, which functions within the ubiquitin-mediated degradation system to recognize...
Autores principales: | Chen, Minyong, Shi, Xiaofeng, Duke, Rebecca M., Ruse, Cristian I., Dai, Nan, Taron, Christopher H., Samuelson, James C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457524/ https://www.ncbi.nlm.nih.gov/pubmed/28534482 http://dx.doi.org/10.1038/ncomms15487 |
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