Cargando…

Novel APC gene mutations associated with protein alteration in diffuse type gastric cancer

BACKGROUND: The role of adenomatous polyposis coli (APC) gene in mitosis might be critical for regulation of genomic stability and chromosome segregation. APC gene mutations have been associated to have a role in colon cancer and since gastric and colon tumors share some common genetic lesions, it i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ghatak, Souvik, Chakraborty, Payel, Sarkar, Sandeep Roy, Chowdhury, Biswajit, Bhaumik, Arup, Kumar, Nachimuthu Senthil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457612/ https://www.ncbi.nlm.nih.gov/pubmed/28576136 http://dx.doi.org/10.1186/s12881-017-0427-2

Ejemplares similares

Panel of significant risk factors predicts early stage gastric cancer and indication of poor prognostic association with pathogens and microsatellite stability
por: Chakraborty, Payel, et al.
Publicado: (2021)

Polymorphisms in ADH1B and ALDH2 genes associated with the increased risk of gastric cancer in West Bengal, India
por: Ghosh, Sudakshina, et al.
Publicado: (2017)

Mitochondrial complex I and V gene polymorphisms in type II diabetes mellitus among high risk Mizo-Mongoloid population, Northeast India
por: Lalrohlui, Freda, et al.
Publicado: (2016)

Fermented pork fat (Sa-um) and lifestyle risk factors as potential indicators for type 2 diabetes among the Mizo population, Northeast India
por: Lalrohlui, Freda, et al.
Publicado: (2021)

Influence of Micronutrients on the Food Consumption Rate and Silk Production of Bombyx mori (Lepidoptera: Bombycidae) Reared on Mulberry Plants Grown in a Mountainous Agro-Ecological Condition
por: Ruth, Lalfelpuii, et al.
Publicado: (2019)

LGR5 Expression Predicting Poor Prognosis Is Negatively Correlated with WNT5A in Colon Cancer
por: Mehdawi, Lubna M., et al.
Publicado: (2023)

Aggressive gastric cancer in a patient with an APC mutation and a monoallelic MYH mutation
por: Wise, Paul, et al.
Publicado: (2010)

Infrequent alterations of the APC and MCC genes in gastric cancers from British patients.
por: Sud, R., et al.
Publicado: (1996)

An intestinal stem cell niche in Apc mutated neoplasia targetable by CtBP inhibition
por: Chawla, Ayesha T., et al.
Publicado: (2018)

B-HEX pupil expander in vitreoretinal surgery – A case series
por: Chakraborty, Debdulal, et al.
Publicado: (2020)

ESX secretion system: The gatekeepers of mycobacterial survivability and pathogenesis
por: ROY, SADHANA, et al.
Publicado: (2020)

APC(+/−) alters colonic fibroblast proteome in FAP
por: Patel, Bhavinkumar B., et al.
Publicado: (2011)

Prevalence of APC and PTEN Alterations in Urachal Cancer
por: Nagy, Nikolett, et al.
Publicado: (2020)

Exploring the Inclusion Complex of a Drug (Umbelliferone) with α-Cyclodextrin Optimized by Molecular Docking and Increasing Bioavailability with Minimizing the Doses in Human Body
por: Roy, Niloy, et al.
Publicado: (2020)

APC and MUTYH Analysis in FAP Patients: A Novel Mutation in APC Gene and Genotype-Phenotype Correlation
por: D’Elia, Giovanna, et al.
Publicado: (2018)

The Mycobacterial MsDps2 Protein Is a Nucleoid-Forming DNA Binding Protein Regulated by Sigma Factors σ(A) and σ(B)
por: Saraswathi, Ramachandran, et al.
Publicado: (2009)

HER2 and APC Mutations Promote Altered Crypt-Villus Morphology and Marked Hyperplasia in the Intestinal Epithelium
por: Murray, Elisa, et al.
Publicado: (2021)

Apoptotic and Autophagic Effects of Sesbania grandiflora Flowers in Human Leukemic Cells
por: Roy, Rajneeta, et al.
Publicado: (2013)

APC gene is modulated by hsa-miR-135b-5p in both diffuse and intestinal gastric cancer subtypes
por: Magalhães, Leandro, et al.
Publicado: (2018)

Comparative transcriptome analysis of SARS-CoV, MERS-CoV, and SARS-CoV-2 to identify potential pathways for drug repurposing
por: Krishnamoorthy, Pandikannan, et al.
Publicado: (2021)

The case of the youngest infant with hepatoblastoma with APC gene mutation
por: Krawczuk-Rybak, Maryna, et al.
Publicado: (2012)

Recurrent APC gene mutations in Polish FAP families
por: Pławski, Andrzej, et al.
Publicado: (2007)

Analysis of APC mutation in human ameloblastoma and clinical significance
por: Li, Ning, et al.
Publicado: (2016)

TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis
por: Van Nieuwenhuysen, Tom, et al.
Publicado: (2015)

Psychosocial morbidity among children with type-1 diabetes mellitus
por: Chatterjee, Subhankar, et al.
Publicado: (2020)

Biophysical evaluation to categorize pathogenicity of cancer-predisposing mutations identified in the BARD1 BRCT domain
por: Choudhary, Rajan Kumar, et al.
Publicado: (2018)

Analysis of aminoacids pattern in receptor tyrosine kinase using Boolean Association Rule
por: Kalita, Pranjal, et al.
Publicado: (2012)

Resveratrol Regulates Antioxidant Status, Inhibits Cytokine Expression and Restricts Apoptosis in Carbon Tetrachloride Induced Rat Hepatic Injury
por: Roy, Souvik, et al.
Publicado: (2011)

A potent betulinic acid analogue ascertains an antagonistic mechanism between autophagy and proteasomal degradation pathway in HT-29 cells
por: Dutta, Debasmita, et al.
Publicado: (2016)

GAPDH and PUM1: Optimal Housekeeping Genes for Quantitative Polymerase Chain Reaction-Based Analysis of Cancer Stem Cells and Epithelial-Mesenchymal Transition Gene Expression in Rectal Tumors
por: Vermani, Litika, et al.
Publicado: (2020)

The Somatic Mutation Hit on Top of Genetic APC mutations Cause Skin Tumor()
por: Niu, Ting, et al.
Publicado: (2019)

APC gene mutations and colorectal adenomatosis in familial adenomatous polyposis
por: Ficari, F, et al.
Publicado: (2000)

Mutation-negative FAP patients with mRNA defects of APC
por: Condie, Michelle W, et al.
Publicado: (2010)

Apc Mutation Enhances PyMT-Induced Mammary Tumorigenesis
por: Prosperi, Jenifer R., et al.
Publicado: (2011)

Attenuated familial adenomatous polyposis with desmoids caused by an APC mutation
por: Ikenoue, Tsuneo, et al.
Publicado: (2015)

Lipid profiling of mouse intestinal organoids for studying APC mutations
por: Jukes, Zoë, et al.
Publicado: (2021)

Heterozygous APC germline mutations impart predisposition to colorectal cancer
por: Preisler, Livia, et al.
Publicado: (2021)

Sporadic adamantinomatous craniopharyngioma with double-hit somatic APC mutations
por: Hong, Christopher S, et al.
Publicado: (2021)

Mutational inactivation of Apc in the intestinal epithelia compromises cellular organisation
por: Rannikmae, Helena, et al.
Publicado: (2021)

APC mutation correlated with poor response of immunotherapy in colon cancer
por: Li, Bing, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_02bnlnhek3dh63uot63s5t8nnt