Genetic determinants of inherited susceptibility to hypercholesterolemia – a comprehensive literature review

Hypercholesterolemia is a strong determinant of mortality and morbidity associated with cardiovascular diseases and a major contributor to the global disease burden. Mutations in four genes (LDLR, APOB, PCSK9 and LDLRAP1) account for the majority of cases with familial hypercholesterolemia. However,...

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Detalles Bibliográficos
Autores principales: Paththinige, CS, Sirisena, ND, Dissanayake, VHW
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457620/
https://www.ncbi.nlm.nih.gov/pubmed/28577571
http://dx.doi.org/10.1186/s12944-017-0488-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457620/
https://www.ncbi.nlm.nih.gov/pubmed/28577571
http://dx.doi.org/10.1186/s12944-017-0488-4

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