Cargando…
ZAR1 is a novel epigenetically inactivated tumour suppressor in lung cancer
BACKGROUND: Lung cancer is the leading cause of cancer-related deaths with 1.8 million new cases each year and poor 5-year prognosis. Promoter hypermethylation of tumour suppressors leads to their inactivation and thereby can promote cancer development and progression. RESULTS: In this study, we ana...
Autores principales: | Richter, Antje M., Kiehl, Steffen, Köger, Nicole, Breuer, Janina, Stiewe, Thorsten, Dammann, Reinhard H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457737/ https://www.ncbi.nlm.nih.gov/pubmed/28588743 http://dx.doi.org/10.1186/s13148-017-0360-4 |
Ejemplares similares
-
Epigenetic therapy of novel tumour suppressor ZAR1 and its cancer biomarker function
por: Deutschmeyer, Verena, et al.
Publicado: (2019) -
Epigenetic Inactivation of the Tumor Suppressor IRX1 Occurs Frequently in Lung Adenocarcinoma and Its Silencing Is Associated with Impaired Prognosis
por: Küster, Miriam M., et al.
Publicado: (2020) -
Muerte al zar/
por: Williams, Andrew 1970-
Publicado: (2011) -
The tumor suppressor RASSF1A induces the YAP1 target gene ANKRD1 that is epigenetically inactivated in human cancers and inhibits tumor growth
por: Jiménez, Adriana P., et al.
Publicado: (2017) -
El loco del zar /
por: Kross, Jaan
Publicado: (1992)