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Antioxidant Treatment Induces Hyperactivation of the HPA Axis by Upregulating ACTH Receptor in the Adrenal and Downregulating Glucocorticoid Receptors in the Pituitary
Glucocorticoid (GC) production is physiologically regulated through a negative feedback loop mediated by the GC, which appear disrupted in several pathological conditions. The inability to perform negative feedback of the hypothalamus-pituitary-adrenal (HPA) axis in several diseases is associated wi...
Autores principales: | Prevatto, Jessika P., Torres, Rafael C., Diaz, Bruno L., Silva, Patrícia M. R. e, Martins, Marco A., Carvalho, Vinicius F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457771/ https://www.ncbi.nlm.nih.gov/pubmed/28607630 http://dx.doi.org/10.1155/2017/4156361 |
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