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Mitochondrial Transfer from Wharton's Jelly Mesenchymal Stem Cell to MERRF Cybrid Reduces Oxidative Stress and Improves Mitochondrial Bioenergetics
Myoclonus epilepsy associated with ragged-red fibers (MERRF) is a maternally inherited mitochondrial disease affecting neuromuscular functions. Mt.8344A>G mutation in mitochondrial DNA (mtDNA) is the most common cause of MERRF syndrome and has been linked to an increase in reactive oxygen species...
Autores principales: | Chuang, Yao-Chung, Liou, Chia-Wei, Chen, Shang-Der, Wang, Pei-Wen, Chuang, Jiin-Haur, Tiao, Mao-Meng, Hsu, Te-Yao, Lin, Hung-Yu, Lin, Tsu-Kung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457778/ https://www.ncbi.nlm.nih.gov/pubmed/28607632 http://dx.doi.org/10.1155/2017/5691215 |
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