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Assembly and characterization of heterochromatin and euchromatin on human artificial chromosomes

BACKGROUND: Human centromere regions are characterized by the presence of alpha-satellite DNA, replication late in S phase and a heterochromatic appearance. Recent models propose that the centromere is organized into conserved chromatin domains in which chromatin containing CenH3 (centromere-specifi...

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Detalles Bibliográficos
Autores principales: Grimes, Brenda R, Babcock, Jennifer, Rudd, M Katharine, Chadwick, Brian, Willard, Huntington F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545780/
https://www.ncbi.nlm.nih.gov/pubmed/15535865
http://dx.doi.org/10.1186/gb-2004-5-11-r89

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