Technical Limitations of the C1q Single-Antigen Bead Assay to Detect Complement Binding HLA-Specific Antibodies

BACKGROUND: Solid-phase assays to distinguish complement binding from noncomplement binding HLA-specific antibodies have been introduced, but technical limitations may compromise their interpretation. We have examined the extent to which C1q-binding to HLA-class I single-antigen beads (SAB) is influ...

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Detalles Bibliográficos
Autores principales: Taylor, Craig J., Kosmoliaptsis, Vasilis, Martin, Jessie, Knighton, Graham, Mallon, Dermot, Bradley, J. Andrew, Peacock, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Original Clinical Science—General: Antibodies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457814/
https://www.ncbi.nlm.nih.gov/pubmed/27306532
http://dx.doi.org/10.1097/TP.0000000000001270

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