Cargando…

Organ-Specific Differences in Endothelial Permeability-Regulating Molecular Responses in Mouse and Human Sepsis

In patients with sepsis-induced multi-organ dysfunction syndrome, diverging patterns of oedema formation and loss of function in organs such as lung and kidney suggest that endothelial permeability-regulating molecular responses are differentially regulated. This potential differential regulation ha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aslan, Adnan, van Meurs, Matijs, Moser, Jill, Popa, Eliane R., Jongman, Rianne M., Zwiers, Peter J., Molema, Grietje, Zijlstra, Jan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2017
Materias:	Basic Science Aspects
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457831/ https://www.ncbi.nlm.nih.gov/pubmed/28151770 http://dx.doi.org/10.1097/SHK.0000000000000841

Ejemplares similares

Partial Deletion of Tie2 Affects Microvascular Endothelial Responses to Critical Illness in A Vascular Bed and Organ-Specific Way
por: Jongman, Rianne M., et al.
Publicado: (2019)

Early Heterogenic Response of Renal Microvasculature to Hemorrhagic Shock/Resuscitation and the Influence of NF-κB Pathway Blockade
por: Yan, Rui, et al.
Publicado: (2019)

Heterogenous Renal Injury Biomarker Production Reveals Human Sepsis-Associated Acute Kidney Injury Subtypes
por: Jou-Valencia, Daniela, et al.
Publicado: (2019)

Low Serum Angiopoietin-1, High Serum Angiopoietin-2, and High Ang-2/Ang-1 Protein Ratio are Associated with Early Onset Sepsis in Surinamese Newborns
por: Zonneveld, Rens, et al.
Publicado: (2017)

Reduced Tie2 in Microvascular Endothelial Cells Is Associated with Organ-Specific Adhesion Molecule Expression in Murine Health and Endotoxemia
por: Zwiers, Peter J., et al.
Publicado: (2023)

Pattern of tamoxifen-induced Tie2 deletion in endothelial cells in mature blood vessels using endo SCL-Cre-ERT transgenic mice
por: Zwiers, Peter J., et al.
Publicado: (2022)

Kidney histopathology in lethal human sepsis
por: Aslan, Adnan, et al.
Publicado: (2018)

Serum concentrations of endothelial cell adhesion molecules and their shedding enzymes and early onset sepsis in newborns in Suriname
por: Zonneveld, Rens, et al.
Publicado: (2018)

The renal angiopoietin/Tie2 system in lethal human sepsis
por: Aslan, Adnan, et al.
Publicado: (2014)

Unlocking the Untapped Potential of Endothelial Kinase and Phosphatase Involvement in Sepsis for Drug Treatment Design
por: Luxen, Matthijs, et al.
Publicado: (2022)

Unique miRNome and transcriptome profiles underlie microvascular heterogeneity in mouse kidney
por: Luxen, Matthijs, et al.
Publicado: (2023)

Angiopoietin/Tie2 Dysbalance Is Associated with Acute Kidney Injury after Cardiac Surgery Assisted by Cardiopulmonary Bypass
por: Jongman, Rianne M., et al.
Publicado: (2015)

Renal Klotho is Reduced in Septic Patients and Pretreatment With Recombinant Klotho Attenuates Organ Injury in Lipopolysaccharide-Challenged Mice
por: Jou-Valencia, Daniela, et al.
Publicado: (2018)

Pharmacological inhibition of protein tyrosine kinases axl and fyn reduces TNF-α-induced endothelial inflammatory activation in vitro
por: Ellermann, Sophie F., et al.
Publicado: (2022)

Endothelium-targeted delivery of dexamethasone by anti-VCAM-1 SAINT-O-Somes in mouse endotoxemia
por: Li, Ranran, et al.
Publicado: (2018)

Identification of LPS-Activated Endothelial Subpopulations With Distinct Inflammatory Phenotypes and Regulatory Signaling Mechanisms
por: Dayang, Erna-Zulaikha, et al.
Publicado: (2019)

Plasma from patients undergoing coronary artery bypass graft surgery does not activate endothelial cells under shear stress in vitro
por: Ellermann, Sophie F., et al.
Publicado: (2021)

Commentary: Precision Immunotherapy for Sepsis
por: Zijlstra, Jan G., et al.
Publicado: (2019)

LACTATE IMPAIRS VASCULAR PERMEABILITY BY INHIBITING HSPA12B EXPRESSION VIA GPR81-DEPENDENT SIGNALING IN SEPSIS
por: Fan, Min, et al.
Publicado: (2022)

Time course of angiopoietin-2 release during experimental human endotoxemia and sepsis
por: Kümpers, Philipp, et al.
Publicado: (2009)

Bench-to-bedside review: Angiopoietin signalling in critical illness – a future target?
por: van Meurs, Matijs, et al.
Publicado: (2009)

A MODIFIED SURGICAL SEPSIS MODEL SATISFYING SEPSIS-3 AND HAVING HIGH CONSISTENCY OF MORTALITY
por: Wang, Jiebo, et al.
Publicado: (2023)

EFFECT OF IRRIGATION FLUID COMPOSITION ON HEMOSTASIS IN MOUSE BLEEDING MODELS
por: Alsaadi, Nijmeh, et al.
Publicado: (2022)

SUPPLEMENTATION WITH NICOTINAMIDE RIBOSIDE ATTENUATES T CELL EXHAUSTION AND IMPROVES SURVIVAL IN SEPSIS
por: Zhao, Guang-ju, et al.
Publicado: (2023)

Full Activation of CD4(+) T Cells Early During Sepsis Requires Specific Antigen
por: Schmoeckel, Katrin, et al.
Publicado: (2015)

Omeprazole Increases Survival Through the Inhibition of Inflammatory Mediaters in Two Rat Sepsis Models
por: Kotsuka, Masaya, et al.
Publicado: (2022)

HIGH-MOLECULAR-WEIGHT HYALURONAN—A POTENTIAL ADJUVANT TO FLUID RESUSCITATION IN ABDOMINAL SEPSIS?
por: Barrueta Tenhunen, Annelie, et al.
Publicado: (2023)

Pyruvate-Driven Oxidative Phosphorylation is Downregulated in Sepsis-Induced Cardiomyopathy: A Study of Mitochondrial Proteome
por: Shimada, Briana K., et al.
Publicado: (2022)

LOW DOSE OF ESMOLOL ATTENUATES SEPSIS-INDUCED IMMUNOSUPPRESSION VIA MODULATING T-LYMPHOCYTE APOPTOSIS AND DIFFERENTIATION
por: Ma, Ying, et al.
Publicado: (2023)

Blast Wave Exposure to the Extremities Causes Endothelial Activation and Damage
por: Spear, Abigail M., et al.
Publicado: (2015)

sEH Inhibitor Tppu Ameliorates Cecal Ligation and Puncture-Induced Sepsis by Regulating Macrophage Functions
por: Chen, Zhihui, et al.
Publicado: (2020)

Organotypic heterogeneity in microvascular endothelial cell responses in sepsis—a molecular treasure trove and pharmacological Gordian knot
por: Cleuren, Audrey, et al.
Publicado: (2023)

SEPSIS LEADS TO IMPAIRED MITOCHONDRIAL CALCIUM UPTAKE AND SKELETAL MUSCLE WEAKNESS BY REDUCING THE MICU1:MCU PROTEIN RATIO
por: Li, Xuexin, et al.
Publicado: (2023)

Mesenchymal Stem/Stromal Cells Increase Cardiac miR-187-3p Expression in a Polymicrobial Animal Model of Sepsis
por: Ektesabi, Amin M., et al.
Publicado: (2021)

Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model
por: Tamura, Tomoyoshi, et al.
Publicado: (2020)

Endothelial Nox2 Limits Systemic Inflammation and Hypotension in Endotoxemia by Controlling Expression of Toll-Like Receptor 4
por: Trevelin, Silvia Cellone, et al.
Publicado: (2021)

Noninvasive Imaging of Stored Red Blood Cell-Transfusion Aggravating Sepsis-Induced Liver Injury Associated with Increased Activation of M1-Polarized Kupffer Cells
por: Wu, Tao, et al.
Publicado: (2017)

Knockdown of TFPI-Anchored Endothelial Cells Exacerbates Lipopolysaccharide-Induced Acute Lung Injury Via NF-κB Signaling Pathway
por: Wang, Bao Q., et al.
Publicado: (2019)

Comparison of Noninvasive pH and Blood Lactate as Predictors of Mortality in a Swine Hemorrhagic Shock with Restricted Volume Resuscitation Model
por: Soller, Babs, et al.
Publicado: (2015)

A human model of intra-abdominal hypertension: even slightly elevated pressures lead to increased acute systemic inflammation and signs of acute kidney injury
por: Smit, Marije, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_2kvc9g4egmteaaq2fug5p7kano