GOToolBox: functional analysis of gene datasets based on Gene Ontology

We have developed methods and tools based on the Gene Ontology (GO) resource allowing the identification of statistically over- or under-represented terms in a gene dataset; the clustering of functionally related genes within a set; and the retrieval of genes sharing annotations with a query gene. G...

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Detalles Bibliográficos
Autores principales: Martin, David, Brun, Christine, Remy, Elisabeth, Mouren, Pierre, Thieffry, Denis, Jacq, Bernard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545796/
https://www.ncbi.nlm.nih.gov/pubmed/15575967
http://dx.doi.org/10.1186/gb-2004-5-12-r101
Descripción
Sumario:We have developed methods and tools based on the Gene Ontology (GO) resource allowing the identification of statistically over- or under-represented terms in a gene dataset; the clustering of functionally related genes within a set; and the retrieval of genes sharing annotations with a query gene. GO annotations can also be constrained to a slim hierarchy or a given level of the ontology. The source codes are available upon request, and distributed under the GPL license.

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