Cargando…

GOToolBox: functional analysis of gene datasets based on Gene Ontology

We have developed methods and tools based on the Gene Ontology (GO) resource allowing the identification of statistically over- or under-represented terms in a gene dataset; the clustering of functionally related genes within a set; and the retrieval of genes sharing annotations with a query gene. G...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin, David, Brun, Christine, Remy, Elisabeth, Mouren, Pierre, Thieffry, Denis, Jacq, Bernard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545796/
https://www.ncbi.nlm.nih.gov/pubmed/15575967
http://dx.doi.org/10.1186/gb-2004-5-12-r101
_version_ 1782122217375531008
author Martin, David
Brun, Christine
Remy, Elisabeth
Mouren, Pierre
Thieffry, Denis
Jacq, Bernard
author_facet Martin, David
Brun, Christine
Remy, Elisabeth
Mouren, Pierre
Thieffry, Denis
Jacq, Bernard
author_sort Martin, David
collection PubMed
description We have developed methods and tools based on the Gene Ontology (GO) resource allowing the identification of statistically over- or under-represented terms in a gene dataset; the clustering of functionally related genes within a set; and the retrieval of genes sharing annotations with a query gene. GO annotations can also be constrained to a slim hierarchy or a given level of the ontology. The source codes are available upon request, and distributed under the GPL license.
format Text
id pubmed-545796
institution National Center for Biotechnology Information
language English
publishDate 2004
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-5457962005-01-27 GOToolBox: functional analysis of gene datasets based on Gene Ontology Martin, David Brun, Christine Remy, Elisabeth Mouren, Pierre Thieffry, Denis Jacq, Bernard Genome Biol Software We have developed methods and tools based on the Gene Ontology (GO) resource allowing the identification of statistically over- or under-represented terms in a gene dataset; the clustering of functionally related genes within a set; and the retrieval of genes sharing annotations with a query gene. GO annotations can also be constrained to a slim hierarchy or a given level of the ontology. The source codes are available upon request, and distributed under the GPL license. BioMed Central 2004 2004-11-26 /pmc/articles/PMC545796/ /pubmed/15575967 http://dx.doi.org/10.1186/gb-2004-5-12-r101 Text en Copyright © 2004 Martin et al; licensee BioMed Central Ltd.
spellingShingle Software
Martin, David
Brun, Christine
Remy, Elisabeth
Mouren, Pierre
Thieffry, Denis
Jacq, Bernard
GOToolBox: functional analysis of gene datasets based on Gene Ontology
title GOToolBox: functional analysis of gene datasets based on Gene Ontology
title_full GOToolBox: functional analysis of gene datasets based on Gene Ontology
title_fullStr GOToolBox: functional analysis of gene datasets based on Gene Ontology
title_full_unstemmed GOToolBox: functional analysis of gene datasets based on Gene Ontology
title_short GOToolBox: functional analysis of gene datasets based on Gene Ontology
title_sort gotoolbox: functional analysis of gene datasets based on gene ontology
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545796/
https://www.ncbi.nlm.nih.gov/pubmed/15575967
http://dx.doi.org/10.1186/gb-2004-5-12-r101
work_keys_str_mv AT martindavid gotoolboxfunctionalanalysisofgenedatasetsbasedongeneontology
AT brunchristine gotoolboxfunctionalanalysisofgenedatasetsbasedongeneontology
AT remyelisabeth gotoolboxfunctionalanalysisofgenedatasetsbasedongeneontology
AT mourenpierre gotoolboxfunctionalanalysisofgenedatasetsbasedongeneontology
AT thieffrydenis gotoolboxfunctionalanalysisofgenedatasetsbasedongeneontology
AT jacqbernard gotoolboxfunctionalanalysisofgenedatasetsbasedongeneontology