“Chronic myelogenous leukemia in primary blast crisis” rather than “de novo BCR‐ABL1‐positive acute myeloid leukemia”

Differentiating chronic myelogenous leukemia in primary blast crisis (CML‐BC) from de novo BCR‐ABL1‐positive acute myeloid leukemia (AML) is a diagnostic challenge with therapeutic consequences. In our case, a basophilia, the presence of the Philadelphia chromosome in all metaphases and the strict e...

Descripción completa

Detalles Bibliográficos
Autores principales: Pastoret, Cedric, Houot, Roch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458010/
https://www.ncbi.nlm.nih.gov/pubmed/28588805
http://dx.doi.org/10.1002/ccr3.937
_version_ 1783241662593499136
author Pastoret, Cedric
Houot, Roch
author_facet Pastoret, Cedric
Houot, Roch
author_sort Pastoret, Cedric
collection PubMed
description Differentiating chronic myelogenous leukemia in primary blast crisis (CML‐BC) from de novo BCR‐ABL1‐positive acute myeloid leukemia (AML) is a diagnostic challenge with therapeutic consequences. In our case, a basophilia, the presence of the Philadelphia chromosome in all metaphases and the strict exclusion of molecular hallmarks of AML lead us to retain the diagnosis of CML‐BC rather than BCR‐ABL1+ AML.
format Online
Article
Text
id pubmed-5458010
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-54580102017-06-06 “Chronic myelogenous leukemia in primary blast crisis” rather than “de novo BCR‐ABL1‐positive acute myeloid leukemia” Pastoret, Cedric Houot, Roch Clin Case Rep Case Reports Differentiating chronic myelogenous leukemia in primary blast crisis (CML‐BC) from de novo BCR‐ABL1‐positive acute myeloid leukemia (AML) is a diagnostic challenge with therapeutic consequences. In our case, a basophilia, the presence of the Philadelphia chromosome in all metaphases and the strict exclusion of molecular hallmarks of AML lead us to retain the diagnosis of CML‐BC rather than BCR‐ABL1+ AML. John Wiley and Sons Inc. 2017-04-04 /pmc/articles/PMC5458010/ /pubmed/28588805 http://dx.doi.org/10.1002/ccr3.937 Text en © 2017 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Pastoret, Cedric
Houot, Roch
“Chronic myelogenous leukemia in primary blast crisis” rather than “de novo BCR‐ABL1‐positive acute myeloid leukemia”
title “Chronic myelogenous leukemia in primary blast crisis” rather than “de novo BCR‐ABL1‐positive acute myeloid leukemia”
title_full “Chronic myelogenous leukemia in primary blast crisis” rather than “de novo BCR‐ABL1‐positive acute myeloid leukemia”
title_fullStr “Chronic myelogenous leukemia in primary blast crisis” rather than “de novo BCR‐ABL1‐positive acute myeloid leukemia”
title_full_unstemmed “Chronic myelogenous leukemia in primary blast crisis” rather than “de novo BCR‐ABL1‐positive acute myeloid leukemia”
title_short “Chronic myelogenous leukemia in primary blast crisis” rather than “de novo BCR‐ABL1‐positive acute myeloid leukemia”
title_sort “chronic myelogenous leukemia in primary blast crisis” rather than “de novo bcr‐abl1‐positive acute myeloid leukemia”
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458010/
https://www.ncbi.nlm.nih.gov/pubmed/28588805
http://dx.doi.org/10.1002/ccr3.937
work_keys_str_mv AT pastoretcedric chronicmyelogenousleukemiainprimaryblastcrisisratherthandenovobcrabl1positiveacutemyeloidleukemia
AT houotroch chronicmyelogenousleukemiainprimaryblastcrisisratherthandenovobcrabl1positiveacutemyeloidleukemia

Ejemplares similares