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Model-independent fluxome profiling from (2)H and (13)C experiments for metabolic variant discrimination
We introduce a conceptually novel method for intracellular fluxome profiling from unsupervised statistical analysis of stable isotope labeling. Without a priori knowledge on the metabolic system, we identified characteristic flux fingerprints in 10 Bacillus subtilis mutants from 132 (2)H and (13)C t...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545802/ https://www.ncbi.nlm.nih.gov/pubmed/15575973 http://dx.doi.org/10.1186/gb-2004-5-12-r99 |