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Synthesis and characterization of a novel organic nitrate NDHP: Role of xanthine oxidoreductase-mediated nitric oxide formation

In this report, we describe the synthesis and characterization of 1,3-bis(hexyloxy)propan-2-yl nitrate (NDHP), a novel organic mono nitrate. Using purified xanthine oxidoreductase (XOR), chemiluminescence and electron paramagnetic resonance (EPR) spectroscopy, we found that XOR catalyzes nitric oxid...

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Detalles Bibliográficos
Autores principales:	Zhuge, Zhengbing, Paulo, Luciano L., Jahandideh, Arghavan, Brandão, Maria C.R., Athayde-Filho, Petrônio F., Lundberg, Jon O., Braga, Valdir A., Carlström, Mattias, Montenegro, Marcelo F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458096/ https://www.ncbi.nlm.nih.gov/pubmed/28578274 http://dx.doi.org/10.1016/j.redox.2017.05.014

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