Antigen-specific CD8(+) T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin

The connection between innate and adaptive immunity is best exemplified by antigen presentation. Although antigen-presenting cells (APCs) are required for antigen receptor-mediated T-cell activation, how T-cells feedback to APCs to sustain an antigen-specific immune response is not completely clear....

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Detalles Bibliográficos
Autores principales: Yao, Yikun, Chen, Siyuan, Cao, Mengtao, Fan, Xing, Yang, Tao, Huang, Yin, Song, Xinyang, Li, Yongqin, Ye, Lilin, Shen, Nan, Shi, Yufang, Li, Xiaoxia, Wang, Feng, Qian, Youcun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458103/
https://www.ncbi.nlm.nih.gov/pubmed/28537251
http://dx.doi.org/10.1038/ncomms15402

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