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Predicting disease onset in clinically healthy people

Virtually all human disease is induced by oxidative stress. Oxidative stress, which is caused by toxic environmental exposure, the presence of disease, lifestyle choices, stress, chronic inflammation or combinations of these, is responsible for most disease. Oxidative stress from all sources is addi...

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Autor principal: Zeliger, Harold I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458104/
https://www.ncbi.nlm.nih.gov/pubmed/28652846
http://dx.doi.org/10.1515/intox-2016-0006
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author Zeliger, Harold I.
author_facet Zeliger, Harold I.
author_sort Zeliger, Harold I.
collection PubMed
description Virtually all human disease is induced by oxidative stress. Oxidative stress, which is caused by toxic environmental exposure, the presence of disease, lifestyle choices, stress, chronic inflammation or combinations of these, is responsible for most disease. Oxidative stress from all sources is additive and it is the total oxidative stress from all sources that induces the onset of most disease. Oxidative stress leads to lipid peroxidation, which in turn produces Malondialdehyde. Serum malondialdehyde level is an additive parameter resulting from all sources of oxidative stress and, therefore, is a reliable indicator of total oxidative stress which can be used to predict the onset of disease in clinically asymptomatic individuals and to suggest the need for treatment that can prevent much human disease.
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spelling pubmed-54581042017-06-26 Predicting disease onset in clinically healthy people Zeliger, Harold I. Interdiscip Toxicol Review Article Virtually all human disease is induced by oxidative stress. Oxidative stress, which is caused by toxic environmental exposure, the presence of disease, lifestyle choices, stress, chronic inflammation or combinations of these, is responsible for most disease. Oxidative stress from all sources is additive and it is the total oxidative stress from all sources that induces the onset of most disease. Oxidative stress leads to lipid peroxidation, which in turn produces Malondialdehyde. Serum malondialdehyde level is an additive parameter resulting from all sources of oxidative stress and, therefore, is a reliable indicator of total oxidative stress which can be used to predict the onset of disease in clinically asymptomatic individuals and to suggest the need for treatment that can prevent much human disease. Slovak Toxicology Society SETOX 2016-06 2017-05-17 /pmc/articles/PMC5458104/ /pubmed/28652846 http://dx.doi.org/10.1515/intox-2016-0006 Text en Copyright © 2016 SETOX & Institute of Experimental Pharmacology and Toxicology, SASc. https://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. (CC BY-NC-ND 4.0)
spellingShingle Review Article
Zeliger, Harold I.
Predicting disease onset in clinically healthy people
title Predicting disease onset in clinically healthy people
title_full Predicting disease onset in clinically healthy people
title_fullStr Predicting disease onset in clinically healthy people
title_full_unstemmed Predicting disease onset in clinically healthy people
title_short Predicting disease onset in clinically healthy people
title_sort predicting disease onset in clinically healthy people
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458104/
https://www.ncbi.nlm.nih.gov/pubmed/28652846
http://dx.doi.org/10.1515/intox-2016-0006
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