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Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice
To investigate the effects and mechanism of diosmetin on acute hepatic failure (AHF), an AHF murine model was established through administration of lipopolysaccharides/D-galactosamine (LPS/D-GalN). In vitro, diosmetin scavenged free radicals. In vivo, diosmetin decreased mortality among mice, blocke...
Autores principales: | Yang, You, Gong, Xiao-Bao, Huang, Li-Gua, Wang, Zhen-Xu, Wan, Rong-Zhen, Zhang, Peng, Zhang, Qing-Yan, Chen, Zhu, Zhang, Bao-Shun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458162/ https://www.ncbi.nlm.nih.gov/pubmed/28430612 http://dx.doi.org/10.18632/oncotarget.15413 |
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