Cargando…

Chikusetsu saponin IVa ameliorates high fat diet-induced inflammation in adipose tissue of mice through inhibition of NLRP3 inflammasome activation and NF-κB signaling

Chronic metabolic inflammation in adipose tissue plays an important role in the development of obesity-associated diseases. Our previous study indicated that total saponins of Panax japonicus (SPJ) rhizoma and Chikusetsu saponin V, one main component of SPJ, could exert the anti-oxidative and anti-i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Chengfu, Liu, Chaoqi, Wang, Ting, He, Yumin, Zhou, Zhiyong, Dun, Yaoyan, Zhao, Haixia, Ren, Dongming, Wang, Junjie, Zhang, Changcheng, Yuan, Ding
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458186/ https://www.ncbi.nlm.nih.gov/pubmed/28415686 http://dx.doi.org/10.18632/oncotarget.16052

Ejemplares similares

Preventive effects of total saponins of Panax japonicus on fatty liver fibrosis in mice
por: Yuan, Ding, et al.
Publicado: (2016)

Chikusetsu saponin IVa confers cardioprotection via SIRT1/ERK1/2 and Homer1a pathway
por: Duan, Jialin, et al.
Publicado: (2015)

Regulatory effects of saponins from Panax japonicus on colonic epithelial tight junctions in aging rats
por: Dun, Yaoyan, et al.
Publicado: (2018)

IRS-2/Akt/GSK-3β/Nrf2 Pathway Contributes to the Protective Effects of Chikusetsu Saponin IVa against Lipotoxicity
por: Wang, Lei, et al.
Publicado: (2021)

Saponins from Panax japonicus ameliorate age-related renal fibrosis by inhibition of inflammation mediated by NF-κB and TGF-β1/Smad signaling and suppression of oxidative stress via activation of Nrf2-ARE signaling
por: Gao, Yan, et al.
Publicado: (2021)

Chikusetsu saponin IVa protects pancreatic β cell against intermittent high glucose-induced injury by activating Wnt/β-catenin/TCF7L2 pathway
por: Cui, Jia, et al.
Publicado: (2020)

Icariin Improves Age-Related Testicular Dysfunction by Alleviating Sertoli Cell Injury via Upregulation of the ERα/Nrf2-Signaling Pathway
por: Zhao, Haixia, et al.
Publicado: (2020)

MiR-155/GSK-3β mediates anti-inflammatory effect of Chikusetsusaponin IVa by inhibiting NF-κB signaling pathway in LPS-induced RAW264.7 cell
por: Xin, Yi, et al.
Publicado: (2020)

Chikusetsu Saponin V Attenuates MPP(+)-Induced Neurotoxicity in SH-SY5Y Cells via Regulation of Sirt1/Mn-SOD and GRP78/Caspase-12 Pathways
por: Yuan, Ding, et al.
Publicado: (2014)

Role of NLRP3 Inflammasome in the Progression of NAFLD to NASH
por: Wan, Xingyong, et al.
Publicado: (2016)

Baicalin ameliorates atherosclerosis by inhibiting NLRP3 inflammasome in apolipoprotein E-deficient mice
por: Zhao, Jingfei, et al.
Publicado: (2020)

Biejiajian Pill Ameliorates Diabetes-Associated Atherosclerosis through Inhibition of the NLRP3 Inflammasome
por: Fu, Yu, et al.
Publicado: (2022)

Orientin Ameliorates LPS-Induced Inflammatory Responses through the Inhibitory of the NF-κB Pathway and NLRP3 Inflammasome
por: Xiao, Qingfei, et al.
Publicado: (2017)

Maf1 Ameliorates Sepsis-Associated Encephalopathy by Suppressing the NF-kB/NLRP3 Inflammasome Signaling Pathway
por: Chen, Shenglong, et al.
Publicado: (2020)

Relief Effects of Icariin on Inflammation-Induced Decrease of Tight Junctions in Intestinal Epithelial Cells
por: Li, Yanli, et al.
Publicado: (2022)

Humanin Ameliorates Free Fatty Acid-Induced Endothelial Inflammation by Suppressing the NLRP3 Inflammasome
por: Li, Wenfeng, et al.
Publicado: (2020)

Inhibition of NLRP3 Inflammasome Ameliorates Cerebral Ischemia-Reperfusion Injury in Diabetic Mice
por: Hong, Pu, et al.
Publicado: (2018)

Curcumin Ameliorates Diabetic Nephropathy by Suppressing NLRP3 Inflammasome Signaling
por: Lu, Miaomiao, et al.
Publicado: (2017)

Celastrol ameliorates inflammation through inhibition of NLRP3 inflammasome activation
por: Yu, Xianjun, et al.
Publicado: (2017)

Targeting of NLRP3 inflammasome with gene editing for the amelioration of inflammatory diseases
por: Xu, Congfei, et al.
Publicado: (2018)

NLRP6 Inflammasome Ameliorates Brain Injury after Intracerebral Hemorrhage
por: Wang, Peng-Fei, et al.
Publicado: (2017)

Ketogenic diet ameliorates inflammation by inhibiting the NLRP3 inflammasome in osteoarthritis
por: Kong, Ganggang, et al.
Publicado: (2022)

Ruscogenin Ameliorated Sjögren's Syndrome by Inhibiting NLRP3 Inflammasome Activation
por: He, Jing, et al.
Publicado: (2022)

BRD4 Inhibition Attenuates Inflammatory Pain by Ameliorating NLRP3 Inflammasome-Induced Pyroptosis
por: Hua, Tong, et al.
Publicado: (2022)

LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy
por: Yi, Hong, et al.
Publicado: (2017)

Canagliflozin Ameliorates NLRP3 Inflammasome-Mediated Inflammation Through Inhibiting NF-κB Signaling and Upregulating Bif-1
por: Niu, Yaoyun, et al.
Publicado: (2022)

Qiqilian ameliorates vascular endothelial dysfunction by inhibiting NLRP3-ASC inflammasome activation in vivo and in vitro
por: Luo, Yuan, et al.
Publicado: (2023)

Ginsenoside Rk2, a dehydroprotopanaxadiol saponin, alleviates alcoholic liver disease via regulating NLRP3 and NLRP6 inflammasome signaling pathways in mice
por: Zou, Jian, et al.
Publicado: (2023)

Exosomes Regulate NLRP3 Inflammasome in Diseases
por: Li, Zhangwang, et al.
Publicado: (2022)

Pioglitazone ameliorates glomerular NLRP3 inflammasome activation in apolipoprotein E knockout mice with diabetes mellitus
por: Wang, Yao, et al.
Publicado: (2017)

Salidroside Ameliorates Alzheimer's Disease by Targeting NLRP3 Inflammasome-Mediated Pyroptosis
por: Cai, Yawen, et al.
Publicado: (2022)

Flavonoids Ameliorate Stress-Induced Depression by Preventing NLRP3 Inflammasome Priming
por: Pasinetti, Giulio
Publicado: (2022)

Delayed NLRP3 inflammasome inhibition ameliorates subacute stroke progression in mice
por: Bellut, Maximilian, et al.
Publicado: (2023)

Glibenclamide ameliorates the disrupted blood–brain barrier in experimental intracerebral hemorrhage by inhibiting the activation of NLRP3 inflammasome
por: Xu, Fulin, et al.
Publicado: (2019)

The NLRP6 inflammasome
por: Zheng, Danping, et al.
Publicado: (2020)

Corticosterone Inhibits LPS-Induced NLRP3 Inflammasome Priming in Macrophages by Suppressing Xanthine Oxidase
por: Wu, Ling, et al.
Publicado: (2020)

Targeting Microglial α-Synuclein/TLRs/NF-kappaB/NLRP3 Inflammasome Axis in Parkinson’s Disease
por: Li, Yunna, et al.
Publicado: (2021)

Catalpol ameliorates depressive-like behaviors in CUMS mice via oxidative stress-mediated NLRP3 inflammasome and neuroinflammation
por: Wang, Ya-lin, et al.
Publicado: (2021)

NLRP3 inflammasome activation in response to metals
por: Huang, Wanyi, et al.
Publicado: (2023)

Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-κB signaling and NLRP3 inflammasome activation
por: Peng, Shuang, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_i8i6jhutevleqmsuk71sjk414m