Endosomal sorting and c-Cbl targeting of paxillin to autophagosomes regulate cell-matrix adhesion turnover in human breast cancer cells

Post-translational mechanisms regulating cell-matrix adhesion turnover during cell locomotion are not fully elucidated. In this study, we uncovered an essential role of Y118 site-specific tyrosine phosphorylation of paxillin, an adapter protein of focal adhesion complexes, in paxillin recruitment to...

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Detalles Bibliográficos
Autores principales: Chang, Chia-Hao, Bijian, Krikor, Qiu, Dinghong, Su, Jie, Saad, Amine, Dahabieh, Michael S, Miller, Wilson H, Alaoui-Jamali, Moulay A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458201/
https://www.ncbi.nlm.nih.gov/pubmed/28415719
http://dx.doi.org/10.18632/oncotarget.16105

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