Polyisoprenylated cysteinyl amide inhibitors disrupt actin cytoskeleton organization, induce cell rounding and block migration of non-small cell lung cancer

The malignant potential of Non-Small Cell Lung Cancer (NSCLC) is dependent on cellular processes that promote metastasis. F-actin organization is central to cell migration, invasion, adhesion and angiogenesis, processes involved in metastasis. F-actin remodeling is enhanced by the overexpression and...

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Detalles Bibliográficos
Autores principales: Ntantie, Elizabeth, Fletcher, Jerrine, Amissah, Felix, Salako, Olufisayo O, Nkembo, Augustine T, Poku, Rosemary A, Ikpatt, Francis O, Lamango, Nazarius S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458243/
https://www.ncbi.nlm.nih.gov/pubmed/28423648
http://dx.doi.org/10.18632/oncotarget.15956

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