Invasive Fusobacterium nucleatum activates beta-catenin signaling in colorectal cancer via a TLR4/P-PAK1 cascade

The underlying mechanism of Fusobacterium nucleatum (Fn) in the carcinogenesis of colorectal cancer (CRC) is poorly understood. Here, we examined Fn abundance in CRC tissues, as well as β-catenin, TLR4 and PAK1 protein abundance in Fn positive and Fn negative CRCs. Furthermore, we isolated a strain...

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Detalles Bibliográficos
Autores principales: Chen, Yongyu, Peng, Yan, Yu, Jiahui, Chen, Ting, Wu, Yaxin, Shi, Lei, Li, Qing, Wu, Jiao, Fu, Xiangsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458249/
https://www.ncbi.nlm.nih.gov/pubmed/28423670
http://dx.doi.org/10.18632/oncotarget.15992

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