Tumor hypoxia modulates podoplanin/CCL21 interactions in CCR7+ NK cell recruitment and CCR7+ tumor cell mobilization

Podoplanin (PDPN), an O-glycosylated, transmembrane, mucin-type glycoprotein, is expressed by cancer associated fibroblasts (CAFs). In malignant transformation, PDPN is subjected to changes and its role is yet to be established. Here we show that it is involved in modulating the activity of the CCL2...

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Detalles Bibliográficos
Autores principales: Tejchman, Anna, Lamerant-Fayel, Nathalie, Jacquinet, Jean-Claude, Bielawska-Pohl, Aleksandra, Mleczko-Sanecka, Katarzyna, Grillon, Catherine, Chouaib, Salem, Ugorski, Maciej, Kieda, Claudine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458255/
https://www.ncbi.nlm.nih.gov/pubmed/28416768
http://dx.doi.org/10.18632/oncotarget.16311

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