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Pellino 1 inactivates mitotic spindle checkpoint by targeting BubR1 for ubiquitinational degradation

Aberrant constitutive activation of receptor-mediated downstream signalling plays an active role in the deregulation of cell cycle control. The mitotic spindle checkpoint is important in preventing abnormal mitotic cell cycle with chromosome missegregation from achieving neoplastic aneuploidy. Howev...

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Detalles Bibliográficos
Autores principales:	Park, Jihyun, Park, Hye-Young, Kim, Suhyeon, Kim, Hyun-Soo, Park, Ji Y., Go, Heounjeong, Lee, Chang-Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458268/ https://www.ncbi.nlm.nih.gov/pubmed/28410192 http://dx.doi.org/10.18632/oncotarget.16762

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